Results 201 to 210 of about 1,131,860 (291)

Preventing Protein Self-Association Through Strategic Covalent Modification. [PDF]

J Pept Sci
Chintala S, Friedman SH.
europepmc   +1 more source

Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease. [PDF]

Biochem Biophys Rep, 2021
Alsalahat I, Al-Majdoub ZM, Taha MO, Barber J, Aojula H, Hodson N, Freeman S.   +6 more
europepmc   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Molecular mechanism underlying <i>Oleum Cinnamomi</i>-induced ferroptosis in MRSE via covalent modification of AhpC. [PDF]

Front Pharmacol
Wang J, Wu Z, Chen Q, Yan D, Ling Y, He Y, Jin L, Zhao G, Peng H, Yang D.   +9 more
europepmc   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

Advanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo, So Yun Lim, Dong‐Sung Won, Ji Won Kim, Yubeen Park, Song Hee Kim, Hyemin Lee, Jung‐Min Ahn, Jun‐Kyu Park, Do‐Yoon Kang, Jung‐Hoon Park   +10 more
wiley   +1 more source

Dimeric natural product panepocyclinol A inhibits STAT3 <i>via</i> di-covalent modification. [PDF]

Acta Pharm Sin B
Li L, Wang Y, Wang Y, Li X, Deng Q, Gao F, Lian W, Li Y, Gui F, Wei Y, Zhu SJ, Yun CH, Zhang L, Hu Z, Xu Q, Wu X, Chen L, Zhou D, Zhang J, Xia F, Deng X.   +20 more
europepmc   +1 more source

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source

The Morphological Dependence of PEDOT on the Supporting Electrolytes Used and the Acquisition of Gold Nanoparticles with a View to Their Use in the Covalent Modification of the Ki-67 Antibody. [PDF]

Polymers (Basel)
Hernández LA, Figueroa IDM, Riveros G, Luengo M, Muñoz E.   +4 more
europepmc   +1 more source

Energetic Offset in Organic Solar Cells‐ Importance, Confusion and Outlook

Advanced Materials, EarlyView.
Energetic offsets in organic solar cells (OSCs) remain a subject of debate due to measurement‐ and lab‐dependent discrepancies. This Perspective clarifies the physical origins of these variations and identifies temperature‐dependent electro‐optical methods as a reliable approach to obtain consistent offset values.
Nakul Jain, Xian'e Li, Mats Fahlman, Olle Inganäs, Koen Vandewal, Feng Gao   +5 more
wiley   +1 more source