Results 181 to 190 of about 1,131,860 (291)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Covalent Modification of Proteins by Plant-Derived Natural Products: Proteomic Approaches and Biological Impacts. [PDF]

Proteomics, 2021
Tocmo R, Tocmo R, Tocmo R, Veenstra JP, Huang Y, Johnson JJ.   +5 more
europepmc   +1 more source

A practical method for determining the rate of covalent modification of fragments and leads. [PDF]

Nat Commun
Jeon J, Kholodar SA, Tran BH, Mallinger KE, Erlanson DA, Everley RA.   +5 more
europepmc   +1 more source

Surface Tuning of Wood via Covalent Modification of Its Lignocellulosic Biopolymers with Substituted Benzoates-A Study on Reactivity, Efficiency, and Durability. [PDF]

ACS Omega, 2021
Söftje M, Weingartz T, Plarre R, Gjikaj M, Namyslo JC, Kaufmann DE.   +5 more
europepmc   +1 more source

Multiplexed Detection of Respiratory Viruses Using Surface Plasmon Resonance Spectroscopy With Ultrathin Carbon Nanomembranes

Advanced Healthcare Materials, EarlyView.
An ultrathin azide‐functionalized carbon nanomembrane (N3‐CNM) provides a versatile biointerface for antibody immobilization on gold SPR sensors. Integrated with a multichannel SPR platform, the functionalized surface enables label‐free, simultaneous detection of SARS‐CoV‐2, Influenza A, and RSV antigens, demonstrating the potential of CNM‐based ...
Ghazaleh Eshaghi, Hamid Reza Rasouli, David Kaiser, Tobias Fischer, Katrin Frankenfeld, Abhishek Sharma, Andrey Turchanin   +6 more
wiley   +1 more source

Covalent modification of flaxseed protein isolate by polyphenols and characterization of the structural and functional properties of the conjugates. [PDF]

Food Chem X
Yang F, Li J, Wang J, Gan S, Dong G.
europepmc   +1 more source

Frequency-preference response in covalent modification cycles under substrate sequestration conditions. [PDF]

NPJ Syst Biol Appl, 2021
Szemere JR, Rotstein HG, Ventura AC.
europepmc   +1 more source

Discovery of Covalent Ligands with AlphaFold3 [PDF]

Covalent inhibitors are a prominent modality for research and therapeutic tools. However, a scarcity of computational methods for their discovery slows progress in this field.
Lin, David Yin-wei, Shamir, Yoav, London, Nir, Rogel, Adi, Gabizon, Ronen, Andreotti, Amy   +5 more
core  

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source