Results 181 to 190 of about 2,379,457 (382)

Supplementary Table S2 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification

open access: gold, 2023
Wenyi Sun   +15 more
openalex   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi   +5 more
wiley   +1 more source

Mollugin reacts with phenol thiol but not produce modification on cysteine discovered by a phenol thiol probe

open access: yesFrontiers in Cell and Developmental Biology
Electrophilic compounds from natural products (NPs) and metabolites can covalently modify the cysteines of target proteins to induce biological activities.
Tao Liu   +12 more
doaj   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

open access: yesAdvanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi   +5 more
wiley   +1 more source

Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors. [PDF]

open access: yesACS Pharmacol Transl Sci, 2023
Francisco KR   +11 more
europepmc   +1 more source

Tuning the Selectivity of the CO2 Reduction Reaction by Means of Synergistic Interactions in the Cu, Ag, Ce System

open access: yesAdvanced Functional Materials, EarlyView.
Multi‐metal Cu─Ce─Ag nanoparticles harness synergistic interactions to drive efficient electrochemical CO2 reduction reaction toward C2+ products at high current densities. Ag enhances CO production, Ce modulates Cu oxidation states, and together they boost *CO coverage and local pH to enhance C─C coupling, enabling record C2+ yields with suppressed ...
Nini Zhang   +9 more
wiley   +1 more source

Improvement in Biological Performance of Poly(Lactic Acid)-Based Materials via Single-Point Surface Modification with Glycopolymer

open access: yesSurfaces
As a promising polymer for the production of biomaterials and drug delivery systems, poly(lactic acid) (PLA) is characterized by its relative hydrophobicity, as well as its chemical and biological inertness.
Viktor Korzhikov-Vlakh   +5 more
doaj   +1 more source

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