Results 331 to 340 of about 2,379,457 (382)
Some of the next articles are maybe not open access.
The language of covalent histone modifications
Nature, 2000Histone proteins and the nucleosomes they form with DNA are the fundamental building blocks of eukaryotic chromatin. A diverse array of post-translational modifications that often occur on tail domains of these proteins has been well documented. Although the function of these highly conserved modifications has remained elusive, converging biochemical ...
B D, Strahl, C D, Allis
openaire +2 more sources
Reversible covalent modification of DNA
Archives of Biochemistry and Biophysics, 1974The reaction of bromomethylbenzoyl esters of choline and dimethylaminoethanol with DNA and model compounds led predominantly to phosphotriester formation. In model compounds the phosphotriester formation was verified by uv spectrometry. The bromomethylbenzoyl cationic esters reacted with DNA at room temperature at neutral pH values.
R N, Gohil, A C, Roth, R A, Day
openaire +2 more sources
Targeted Covalent Modification Strategies for Drugging the Undruggable Targets.
Chemical ReviewsThe term "undruggable" refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural, functional, or dynamic properties.
Tomonori Tamura +2 more
semanticscholar +1 more source
Applied Catalysis B: Environmental, 2019
The search of novel visible-light-responsive porous materials is important because they hold great promise for applications in various fields. Herein, we report a novel strategy based on postsynthetic covalent modification for fabrication of hierarchical
Fei Li +8 more
semanticscholar +1 more source
The search of novel visible-light-responsive porous materials is important because they hold great promise for applications in various fields. Herein, we report a novel strategy based on postsynthetic covalent modification for fabrication of hierarchical
Fei Li +8 more
semanticscholar +1 more source
Food Chemistry
Soybean protein isolate was modified with polysaccharides and polyphenols to prepare a natural emulsifier with antioxidant capacity. Physicochemical, structural, interfacial, and functional properties of SPI-SSPS complex were investigated after covalent ...
Chuxin Ke, Liang Li
semanticscholar +1 more source
Soybean protein isolate was modified with polysaccharides and polyphenols to prepare a natural emulsifier with antioxidant capacity. Physicochemical, structural, interfacial, and functional properties of SPI-SSPS complex were investigated after covalent ...
Chuxin Ke, Liang Li
semanticscholar +1 more source
Food Chemistry, 2019
Covalent modification of flaxseed protein isolate by phenolic compounds including flaxseed polyphenols, ferulic acid, and hydroxytyrosol was studied under alkaline condition and in the presence of oxygen.
L. Pham, Bo Wang, B. Zisu, B. Adhikari
semanticscholar +1 more source
Covalent modification of flaxseed protein isolate by phenolic compounds including flaxseed polyphenols, ferulic acid, and hydroxytyrosol was studied under alkaline condition and in the presence of oxygen.
L. Pham, Bo Wang, B. Zisu, B. Adhikari
semanticscholar +1 more source
Regulated covalent modifications of lipid A
Journal of Endotoxin Research, 2001Regulated covalent modifications of lipid A are implicated in virulence of pathogenic Gram-negative bacteria. The Salmonella PhoP/PhoQ-activated gene pagP is required for resistance to cationic antimicrobial peptides and for biosynthesis of hepta-acylated lipid A species containing palmitate.
openaire +2 more sources
Comprehensive Reviews in Food Science and Food Safety, 2020
To improve the quality of meat products is a constant focus for both the meat industry and scientists. As major components in meat protein, the gelation properties of myofibrillar proteins (MPs) predominantly determine the sensory quality and product ...
Xue Zhao, Xinglian Xu, G. Zhou
semanticscholar +1 more source
To improve the quality of meat products is a constant focus for both the meat industry and scientists. As major components in meat protein, the gelation properties of myofibrillar proteins (MPs) predominantly determine the sensory quality and product ...
Xue Zhao, Xinglian Xu, G. Zhou
semanticscholar +1 more source
Covalent modifications of aminophospholipids by 4-hydroxynonenal
Free Radical Biology and Medicine, 1998Lipid oxidation is implicated in a wide range of pathophysiological disorders, which leads to reactive compounds such as aldehydes. Among them 4-hydroxynonenal (4-HNE) reacts strongly with the NH2 groups of amino acids and forms mainly Michael adducts and minor Schiff-base adducts. Such reactions occur also with compounds containing thiol groups.
M, Guichardant +3 more
openaire +2 more sources
Regulation by Covalent Modification
2009The preceding chapter showed that the regulation of enzymatic activity can be carried out through a variety of mechanisms. Regulation involving covalent processes is even more diverse. These processes include various co- and post-translational events such as limited proteolysis and various chemical modifications (glycosylation, carboxylation, ADP ...
Jeannine Yon-Kahn, Guy Hervé
openaire +1 more source