Results 101 to 110 of about 309,621 (292)
Imputation of Missing Clinical Covariates for Downstream Classification Problems [PDF]
, 2023 Benjamin Agbo +4 more
openalex +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Examining the Reliability of Model‐Based Meta‐Analysis (MBMA) Outcomes: A Simulation Study
CPT: Pharmacometrics & Systems PharmacologyModel‐based meta‐analysis (MBMA) can be utilized to synthesize literature data and predict drug efficacy, particularly suitable for constructing external comparator arms for non‐randomized controlled trials (NRCTs).
Jiesen Yu +4 more
doaj +1 more source
The geographic distribution of breast cancer incidence in Massachusetts 1988 to 1997, adjusted for covariates. [PDF]
, 2004 T. Joseph Sheehan +5 more
openalex +1 more source
An Effective Procedure to Improve Covariates Balance for Multiple Groups in Randomized Trials [PDF]
, 2023 Na Li, Zhen Meng
openalex +1 more source
Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg +9 more
wiley +1 more source
Empirical Likelihood Covariate Adjustment for Regression Discontinuity Designs [PDF]
, 2020 Jun Ma, Zhengfei Yu
openalex +1 more source
Arthritis Care &Research, EarlyView.Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry +16 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England +9 more
wiley +1 more source