Results 51 to 60 of about 589,878 (312)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Factors Affecting the Establishment and Growth of Cover Crops Intersown into Maize (Zea mays L.)

Agronomy, 2021
In the North Central USA, intersowing cover crops into standing maize (Zea mays L.) is required to establish plants large enough to afford the benefits of a cover since there is limited favorable weather for cover crop growth after maize harvest.
Mattie B. Schmitt, Marisol Berti, Dulan Samarappuli, Joel K. Ransom   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Cover crop mixture diversity, biomass productivity, weed suppression, and stability.

PLoS ONE, 2019
The diversity-productivity, diversity-invasibility, and diversity-stability hypotheses propose that increasing species diversity should lead, respectively, to increased average biomass productivity, invasion resistance, and stability.
A M Florence, L G Higley, R A Drijber, C A Francis, J L Lindquist   +4 more
doaj   +1 more source

Economic Impacts of Cover Crops for a Missouri Wheat–Corn–Soybean Rotation

Agriculture, 2019
In the United States, agricultural production using row-crop farming has reduced crop diversity. Repeated growing of the same crop in a field reduces soil productivity and increases pests, disease infestations, and weed growth. These negative effects can
Zhen Cai, Ranjith P. Udawatta, Clark J. Gantzer, Shibu Jose, Larry Godsey, Lauren Cartwright   +5 more
doaj   +1 more source

Early Fall Cover Cropping Trial [PDF]

, 2014
Farmers are interested in expanding their cover crop options beyond winter rye. Species of interest include annual ryegrass, oats, vetch, winter pea, tillage radish, and canola.
Cummings, Erica, Darby, Heather, Monahan, Susan, Post, Julian, Ruhl, Lindsey, Ziegler, Sara   +5 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Land cover changes with the development of anaerobic digestion for biogas production in France

GCB Bioenergy, 2023
Anaerobic digestion is developing in various countries worldwide to produce renewable energy. In addition, the resulting digestates provide readily available nutrients when applied to cropping systems as fertilizers. The introduction of a biogas plant on
Florent Levavasseur, Lucie Martin, Léa Boros, Jeanne Cadiou, Marco Carozzi, Philippe Martin, Sabine Houot   +6 more
doaj   +1 more source

Cover Crop Planting Date Trial [PDF]

, 2011
When corn silage is harvested, the entire plant is removed, leaving the soil exposed throughout the winter. Many farmers have started planting cover crops following corn harvest because of increased soil health and fertility.
Cline, Chantel, Cummings, Erica, Darby, Heather, Harwood, Hannah, Madden, Rosalie   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source