Results 11 to 20 of about 338,185 (301)

COVID-19 Drug Treatment in China. [PDF]

Curr Pharmacol Rep, 2020
An unprecedented outbreak of the novel coronavirus in China (COVID-19) occurred in December 2019, and then engulfed the entire world, presenting a significant and urgent threat to global health. Many research institutes have been involved in the development of drugs and vaccines against COVID-19.At present, the strategy of new use of old drugs is ...
Fan L, Jiang S, Yang X, Wang Z, Yang C.
europepmc   +4 more sources

COVID-19: Drug Targets and Potential Treatments [PDF]

Journal of Medicinal Chemistry, 2020
Currently, humans are immersed in a pandemic caused by the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health worldwide. To date, no drug or vaccine has been approved to treat the severe disease caused by this coronavirus, COVID-19.
Gil, Carmen, Ginex, Tiziana, Maestro, Inés, Nozal, Vanesa, Barrado-Gil, Lucía, Cuesta-Geijo, Miguel Ángel, Urquiza, Jesús, Ramírez, David, Alonso, Covadonga, Campillo, Nuria E., Martinez, Ana   +10 more
openaire   +3 more sources

Drug treatment of COVID-19 infection

Current Opinion in Pulmonary Medicine, 2023
Purpose of review COVID-19 pandemic has caused more than 6.6 million deaths globally. Tremendous efforts have been committed for the development of new and repurposed drugs for the treatment of COVID-19. Although different international and national guidelines share consensus in the management of COVID-19 disease with different
Lui, Grace, Guaraldi, Giovanni
openaire   +2 more sources

Drugs for COVID-19 Treatment: A New Challenge

Applied Biochemistry and Biotechnology, 2023
COVID-19 infection is a new disease and our knowledge is limited; day in and day out more and more interesting yet diverse observations are reported by the different research groups from different corners of the world. So, there is an urgent requirement of the invention of some effective and efficient drugs that can carry out the end of the deadly ...
Pratik Talukder, Arunima Saha, Sohini Roy, Gargi Ghosh, Debshikha Dutta Roy, Snejuti Barua   +5 more
openaire   +2 more sources

Drugs Modulating Renin-Angiotensin System in COVID-19 Treatment [PDF]

Biomedicines, 2022
A massive worldwide vaccination campaign constitutes the main tool against the COVID-19 pandemic. However, drug treatments are also necessary. Antivirals are the most frequently considered treatments. However, strategies targeting mechanisms involved in disease aggravation may also be effective. A major role of the tissue renin-angiotensin system (RAS)
Jose L. Labandeira-Garcia, Carmen M. Labandeira, Rita Valenzuela, Maria A. Pedrosa, Aloia Quijano, Ana I. Rodriguez-Perez   +5 more
openaire   +3 more sources

Drug repurposing for the treatment of COVID-19

Journal of Pharmacological Sciences, 2022
Coronavirus disease 2019 (COVID-19) remains prevalent worldwide since its onset was confirmed in Wuhan, China in 2019. Vaccines against the causative virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have shown a preventive effect against the onset and severity of COVID-19, and social and economic activities are gradually recovering.
Yuri Kato, Kazuhiro Nishiyama, Akiyuki Nishimura, Takamasa Noda, Kaori Okabe, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida   +7 more
openaire   +3 more sources

Drug repositioning against COVID-19: a first line treatment [PDF]

Journal of Biomolecular Structure and Dynamics, 2021
COVID-19 disease caused by the SARS-CoV-2 virus has shaken our health and wealth foundations. Although COVID-19 vaccines will become available allowing for attenuation of disease progression rates, distribution of vaccines can create other challenges and delays.
Nousheen, Bibi, Ayesha, Farid, Sana, Gul, Johar, Ali, Farhat, Amin, Umesh, Kalathiya, Ted, Hupp   +6 more
openaire   +2 more sources

COVID-19 OUTCOMES: DRUG TREATMENT OPTIONS

The Bulletin of Contemporary Clinical Medicine, 2021
Background. Since December 2019 there has been a rapid spread of the COVID-19 pandemic across most of the world. This has determined the enormous burden on the global economy. The burden of the new coronavirus infection is determined not only by the costs directly related to the treatment of the acute phase of the disease, but also by the successful
RUSTEM F. KHAMITOV, ALEXANDER V. ZHESTKOV, ALEXANDER A. VIZEL, VASILY D. FEDOTOV   +3 more
openaire   +1 more source

COVID-19 and chronological aging : senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? [PDF]

, 2020
COVID-19, also known as SARS-CoV-2, is a new emerging zoonotic corona virus of the SARS (Severe Acute Respiratory Syndrome) and the MERS (Middle East Respiratory Syndrome) family.
Auwerx, Blagosklonny, Blagosklonny, Blagosklonny, Colasurdo, Colson, Diaz-Quijano, Du, Erusalimsky, Gerontol, Gorospe, Hoffmann, Häkkinen, Jang, Li, Lisanti, Lisanti, Lu, Masternak, Munster, Musso, Nowakowski, Porter, Subbarao, Subbarao, Tanga, Tremblay, Wilce, Yaron, Yusof, Zhang   +30 more
core   +2 more sources

Dexamethasone mitigates remdesivir-induced liver toxicity in human primary hepatocytes and COVID-19 patients

Hepatology Communications, 2023
Background:. Coronavirus disease 2019 (COVID-19) is a global pandemic that has caused more than 600 million cases and over six million deaths worldwide.
Kaiyan Liu, Sydney Stern, Emily L. Heil, Linhao Li, Rula Khairi, Scott Heyward, Hongbing Wang   +6 more
doaj   +1 more source