Results 91 to 100 of about 13,629 (283)

Scanning transmission electron tomography to study virus assembly: Review for the retirement of Paul Walther

open access: yesJournal of Microscopy, EarlyView.
Abstract In this short and popular review, we summarise some of our findings analysing the replication cycles of large DNA viruses using scanning transmission electron tomography (STEM tomography) that we applied in the laboratory of Paul Walther. It is also a tribute to a very kind and expert scientist, who recently retired.
Susanne Wieczorek   +1 more
wiley   +1 more source

Generalized Cowpox Virus Infection in a Patient with HIV, Germany, 2012

open access: yesEmerging Infectious Diseases, 2016
To the Editor: In October 2012, a 35-year-old man with clinical category C HIV infection was admitted to the intensive care unit at the University of Duisburg–Essen, Essen, Germany.
E. Miguel   +6 more
semanticscholar   +1 more source

Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]

open access: yes, 2012
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Amy B. Pedersen   +12 more
core   +1 more source

Re-Assembly and Analysis of an Ancient Variola Virus Genome

open access: yesViruses, 2017
We report a major improvement to the assembly of published short read sequencing data from an ancient variola virus (VARV) genome by the removal of contig-capping sequencing tags and manual searches for gap-spanning reads. The new assembly, together with
Chad Smithson, Jacob Imbery, Chris Upton
doaj   +1 more source

Managing infectious aerosols to counter engineered pandemics: Current recommendations and future research

open access: yesRisk Analysis, EarlyView.
Abstract In the increasingly likely event of an engineered‐virus outbreak or pandemic of catastrophic potential, managing infectious aerosols to reduce transmission will be crucial. Now is the time to start preparing our buildings, public opinion, and regulatory environments for the infectious aerosol management interventions necessary to protect the ...
Adam Lerner   +7 more
wiley   +1 more source

Incongruencies in Vaccinia Virus Phylogenetic Trees

open access: yesComputation, 2014
Over the years, as more complete poxvirus genomes have been sequenced, phylogenetic studies of these viruses have become more prevalent. In general, the results show similar relationships between the poxvirus species; however, some inconsistencies are ...
Chad Smithson   +3 more
doaj   +1 more source

Genome-wide comparison of cowpox viruses reveals a new clade related to Variola virus. [PDF]

open access: yesPLoS ONE, 2013
Zoonotic infections caused by several orthopoxviruses (OPV) like monkeypox virus or vaccinia virus have a significant impact on human health. In Europe, the number of diagnosed infections with cowpox viruses (CPXV) is increasing in animals as well as in ...
Piotr Wojtek Dabrowski   +3 more
doaj   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, Volume 15, Issue 7, Page 1079-1089, July 2025.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu   +12 more
wiley   +1 more source

From the animal house to the field : are there consistent individual differences in immunological profile in wild populations of field voles (Microtus agrestis)? [PDF]

open access: yes, 2017
Inbred mouse strains, living in simple laboratory environments far removed from nature, have been shown to vary consistently in their immune response.
A Gelman   +47 more
core   +6 more sources

Home - About - Disclaimer - Privacy