Results 91 to 100 of about 12,038 (266)
Advanced Science, Volume 13, Issue 2, 9 January 2026.The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
Reconsidering the Argument from Underconsideration [PDF]
, 2012 According to the argument from underconsideration, since theory evaluation is comparative, and since scientists do not have good reasons to believe that they are epistemically privileged, it is unlikely that our best theories are true.
Mizrahi, Moti
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Microglial VRK2 Regulates Astrocytic GABA Synthesis and Tonic Inhibition in the Thalamus
Glia, Volume 74, Issue 1, January 2026.In Vrk2‐deficient mice, tonic GABA inhibition is reduced in the mediodorsal thalamus due to impaired astrocytic GABA synthesis. Microglial VRK2 regulates this process via TNF‐α signaling, revealing a glial–glial mechanism of thalamic inhibition.
Dongsu Lee +10 more
wiley +1 more source
Necrotic Ulcerated Lesion in a Young Boy Caused by Cowpox Virus Infection
Case Reports in Dermatology, 2011 The case presented here points towards the fact that skin lesion observed with a cowpox virus is a rare event but should be considered more as the number of cases has increased in the last years. Cowpox virus (CPXV) belongs to the Poxviridae family.
Anne-Laure Favier +7 more
doaj +1 more source
Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]
, 2015 Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami +40 more
core +3 more sources
Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics
MedComm, Volume 7, Issue 1, January 2026.This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan +14 more
wiley +1 more source
Synthesizing current knowledge on the ecology, phenology, and cultivation of Vaccinium membranaceum
PLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 116-133, January 2026.More than 100 edible native berries grow across Canada's vast territory and are used by over 600 Indigenous Peoples of Canada as a main component of their diet. This research provides critical insights into the ecology, phenology, and cultivation of black huckleberry (Vaccinium membranaceum), a species of significant ecological and cultural importance ...
Mehdi Sharifi +12 more
wiley +1 more source
A Brief Perspective on the Early History of American Infectious Disease Epidemiology [PDF]
, 2013 The early history of epidemiology is closely linked to the history of infectious diseases and can be divided into three distinct periods. The earliest period, which can be traced to the writings of Hippocrates in the third and fourth centuries B.C., was ...
Kass, Edward Harold
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