Results 1 to 10 of about 63,132 (220)
Antiviral activity of the EB peptide against zoonotic poxviruses
Background The EB peptide is a 20-mer that was previously shown to have broad spectrum in vitro activity against several unrelated viruses, including highly pathogenic avian influenza, herpes simplex virus type I, and vaccinia, the prototypic ...
Altmann Sharon E +3 more
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Viral infections of the central nervous system (CNS) lead to a broad range of pathologies. CNS infections with Orthopox viruses have been mainly documented as an adverse reaction to smallpox vaccination with vaccinia virus. To date, there is insufficient
Tomer Israely +12 more
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The resurgence of monkeypox virus (MPXV) has increased demand for validated serological assays to assess exposure and immunity. Cross-reactivity among orthopoxviruses, stemming from high sequence conservation, complicates distinguishing antibody ...
Jonathan C. Reed +12 more
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Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12
Oncolytic viruses are engineered to selectively kill tumor cells and have demonstrated promising results in early-phase clinical trials. To further modulate the innate and adaptive immune system, we generated AZD4820, a vaccinia virus engineered to ...
Cheyne Kurokawa +21 more
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Reemergence of Vaccinia Virus during Zoonotic Outbreak, Pará State, Brazil
In 2010, vaccinia virus caused an outbreak of bovine vaccinia that affected dairy cattle and rural workers in Pará State, Brazil. Genetic analyses identified the virus as distinct from BeAn58058 vaccinia virus (identified in 1960s) and from smallpox ...
Felipe L. de Assis +9 more
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Alternative Routes of Zoonotic Vaccinia Virus Transmission, Brazil
Galileu B. Costa +9 more
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The recent worldwide incidence of mpox infection and concerns about future emerging variants of mpox viruses highlight the need for the development of a new generation of mpox vaccines.
Pengwei Huang +4 more
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La proteína viral VO6 de rotavirus coinmunoprecipita con HSC70 en células MA104
Introducción: los rotavirus son la principal causa de gastroenteritis en niños menores de cinco años. Hasta el momento se desconoce cómo entran estos virus a la célula huésped.
Luz Stella Rodríguez +1 more
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