Results 1 to 10 of about 57,080 (243)

An Update on the Known Host Range of the Brazilian Vaccinia Virus: An Outbreak in Buffalo Calves

open access: yesFrontiers in Microbiology, 2019
Even nearly forty years after the eradication of smallpox, members of the Poxviridae family continue to be the focus of an increasing number of studies.
Abrahão Js   +2 more
exaly   +3 more sources

pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus

open access: yesPharmaceutics, 2022
Oncolytic viruses have emerged as a promising modality in cancer treatment given their high synergy with highly efficient immune checkpoint inhibitors. However, their potency is limited by their rapid in vivo clearance.
Kaelan T. Samoranos   +9 more
doaj   +1 more source

Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses

open access: yesFrontiers in Immunology, 2020
We conducted a large genome-wide association study (GWAS) of the immune responses to primary smallpox vaccination in a combined cohort of 1,653 subjects.
Richard B. Kennedy   +8 more
doaj   +1 more source

Progressive Vaccinia [PDF]

open access: yesClinical Infectious Diseases, 2003
The resumption of smallpox vaccination for health care workers and other first responders has raised concern about the occurrence of complications in people with immunodeficiency disorders, including those infected with human immunodeficiency virus.
Mike, Bray, Mary E, Wright
openaire   +2 more sources

Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research

open access: yesMicroorganisms, 2022
Amidst the ongoing monkeypox outbreak, global awareness has been directed towards the prevention of viral transmission and case management, with the World Health Organization declaring the outbreak a public health emergency of international concern ...
Tolulope Fashina   +4 more
doaj   +1 more source

The Rise and Fall of Modern Plagues

open access: yesMolecular Frontiers Journal, 2020
Millennia separate smallpox, the oldest pandemic, and COVID-19, the newest. Both calamities arose from an opportunistic virus amid human crowding. A vaccine for smallpox existed since the late 18th century, but it took worldwide public health strategy to
G. Terry Sharrer
doaj   +1 more source

Vaccinia virus and peptide-receptor radiotherapy synergize to improve treatment of peritoneal carcinomatosis

open access: yesMolecular Therapy: Oncolytics, 2023
Tumor-specific overexpression of receptors enables a variety of targeted cancer therapies, exemplified by peptide-receptor radiotherapy (PRRT) for somatostatin receptor (SSTR)-positive neuroendocrine tumors.
Kathryn Ottolino-Perry   +9 more
doaj   +1 more source

When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond

open access: yesJournal of Infection in Developing Countries, 2008
The presence of zoonotic poxviruses in nature represents a potential human health risk that has to be re-evaluated by health authorities not only in developing countries, but also in many developed countries.
Nissin Moussatché,1,2 Clarissa R. Damaso,2 and Grant McFadden1
doaj   +3 more sources

Challenges and Achievements in Prevention and Treatment of Smallpox

open access: yesVaccines, 2018
Declaration of smallpox eradication by the WHO in 1980 led to discontinuation of the worldwide vaccination campaign. The increasing percentage of unvaccinated individuals, the existence of its causative infectious agent variola virus (VARV), and the ...
Sharon Melamed, Tomer Israely, Nir Paran
doaj   +1 more source

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