Results 11 to 20 of about 63,132 (220)
African swine fever virus A151R protein antagonizes the antiviral activity of barrier-to-autointegration factor (BAF) by targeting its dsDNA-binding activity [PDF]
Journal of VirologyBarrier-to-autointegration factor (BAF) is a ubiquitous double-stranded DNA-binding protein that compacts DNA and can restrict poxvirus replication in the cytoplasm.
Kepalee Saeng-chuto +3 more
doaj +2 more sources
An Update on the Known Host Range of the Brazilian Vaccinia Virus: An Outbreak in Buffalo Calves
Frontiers in Microbiology, 2019 Even nearly forty years after the eradication of smallpox, members of the Poxviridae family continue to be the focus of an increasing number of studies.
Jônatas Santos Abrahão +2 more
exaly +3 more sources
Arming vaccinia virus for pancreatic cancer oncolytic virotherapy [PDF]
, 2011 PhDVaccinia virus is a 250-300nm enveloped DNA virus from the poxvirus family and is used as a vector for oncolytic viral gene therapy. No unique cell surface receptor has been identified for Vaccinia virus and the reasons for its tropism for cancer ...
Hiley, Crispin
core +4 more sources
Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research
Microorganisms, 2022 Amidst the ongoing monkeypox outbreak, global awareness has been directed towards the prevention of viral transmission and case management, with the World Health Organization declaring the outbreak a public health emergency of international concern ...
Tolulope Fashina +4 more
doaj +1 more source
Pharmaceutics, 2022 Oncolytic viruses have emerged as a promising modality in cancer treatment given their high synergy with highly efficient immune checkpoint inhibitors. However, their potency is limited by their rapid in vivo clearance.
Kaelan T. Samoranos +9 more
doaj +1 more source
Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread
Viruses, 2020 Although orthopoxviruses (OPXV) are known to encode a majority of the genes required for replication in host cells, genome-wide genetic screens have revealed that several host pathways are indispensable for OPXV infection.
Susan Realegeno +10 more
doaj +1 more source
Vaccines, 2020 Background: Vaccinia is known to induce antibody and cellular responses. Plasmablast, circulating follicular helper T (cTFH) cells, cytokine-expressing CD4 T cells, and memory B cells were compared between subcutaneous (SC) and needle-free jet injection (
Evan J. Anderson +13 more
doaj +1 more source
Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses
Frontiers in Immunology, 2020 We conducted a large genome-wide association study (GWAS) of the immune responses to primary smallpox vaccination in a combined cohort of 1,653 subjects.
Richard B. Kennedy +8 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
, 1975 The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
Kruse, F. +5 more
core +1 more source