Results 31 to 40 of about 63,132 (220)

Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats

Frontiers in Immunology, 2021
Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection.
Marsha S. Russell, Sathya N. Thulasi Raman, Caroline Gravel, Wanyue Zhang, Wanyue Zhang, Annabelle Pfeifle, Annabelle Pfeifle, Wangxue Chen, Gary Van Domselaar, David Safronetz, Michael Johnston, Michael Johnston, Simon Sauve, Lisheng Wang, Michael Rosu-Myles, Michael Rosu-Myles, Jingxin Cao, Xuguang Li, Xuguang Li   +18 more
doaj   +1 more source

Vaccinia Scars Associated with Improved Survival among Adults in Rural Guinea-Bissau [PDF]

, 2006
Background: In urban Guinea-Bissau, adults with a vaccinia scar had better survival but also a higher prevalence of HIV-2 infection. We therefore investigated the association between vaccinia scar and survival and HIV infection in a rural area of Guinea ...
Leligdowicz Aleksandra, Maarten Schim van der Loeff, Whittle Hilton, Christine Stabell Benn, Dave, S, Lisse Ida Maria, Tim Vincent, Aleksandra Leligdowicz, Schimvan der Loeff, M, Carlos da Costa, Dave Sangeeta, Mette Lundsby Jensen, Sangeeta Dave, Jensen Mette Lundsby, Vincent Tim, Leligdowicz, A, Lisse, IM, Ravn, H, Ida Maria Lisse, Adam Roth, Whittle, H, Roth Adam, Benn Christine Stabell, Roth, A, Aaby Peter, da Costa Carlos, Henrik Ravn, Peter Aaby, Aaby, P, van der Loeff Maarten Schim, Hilton Whittle, Ravn Henrik, Jensen, ML, da Costa, C, Vincent, T, Benn, CS   +35 more
core   +1 more source

Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]

, 2015
The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason, Rizopoulos, Zaira, Balistreri, G, Kilcher, S, Mercer, J, Syedbasha, M, Kilcher, Samuel, Helenius, Ari, Balistreri, Giuseppe, Rizopoulos, Z, Syedbasha, Mohammedyaseen, Martin, Caroline K., Martin, CK, Helenius, A, Rizopoulos Z, Balistreri G, Syedbasha M, Kilcher S, Martin CK, Mercer J, Helenius A   +20 more
core   +1 more source

In-vitro demonstration of cell-mediated immunity to vaccinia virus in man [PDF]

, 1975
Cell mediated immunity to vaccinia virus in man was studied by lymphocyte transformation. Vaccinia antigen, propagated on BHK-21 and Vero cells, could be used successfully for in-vitro testing after partial purification as well as crude infectious ...
Koszinowski, Ulrich H., Thomssen, R., Volkmann, B.   +2 more
core   +1 more source

LATENT VACCINIA. [PDF]

The Lancet, 1902
n ...
openaire   +2 more sources

When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond

Journal of Infection in Developing Countries, 2008
The presence of zoonotic poxviruses in nature represents a potential human health risk that has to be re-evaluated by health authorities not only in developing countries, but also in many developed countries.
Nissin Moussatché,1,2 Clarissa R. Damaso,2 and Grant McFadden1
doaj   +3 more sources

Challenges and Achievements in Prevention and Treatment of Smallpox

Vaccines, 2018
Declaration of smallpox eradication by the WHO in 1980 led to discontinuation of the worldwide vaccination campaign. The increasing percentage of unvaccinated individuals, the existence of its causative infectious agent variola virus (VARV), and the ...
Sharon Melamed, Tomer Israely, Nir Paran
doaj   +1 more source

Assessing recombinant vaccinia virus as a delivery system for fertility control vaccines in the brushtail possum (Trichosurus vulpecula)

Julius-Kühn-Archiv, 2011
The introduced brushtail possum (Trichosurus vulpecula) is a major threat to native biodiversity and agricultural production in New Zealand. Research on non-lethal management methods is focussed on fertility control, and aims to develop zona pellucida ...
Duckworth, J., Cross, M., Fleming, S., Scobie, S., Whelan, E., Prada, D., Mercer, A., Cowan, P.   +7 more
doaj   +1 more source

Vaccinia Virus: Mechanisms Supporting Immune Evasion and Successful Long-Term Protective Immunity

Viruses
Vaccinia virus is the most successful vaccine in human history and functions as a protective vaccine against smallpox and monkeypox, highlighting the importance of ongoing research into vaccinia due to its genetic similarity to other emergent poxviruses.
Joy Hsu, Suyon Kim, Niroshana Anandasabapathy   +2 more
doaj   +1 more source

Expression of an Efficient Selection Marker Out of a Duplicated Site in the ITRs of a Modified Vaccinia Virus Ankara (MVA)

Vaccines
Background/Objectives: Poxviruses are large DNA viruses that replicate in the host cytoplasm without a nuclear phase. As vaccine vectors, they can package and express large recombinant cassettes from different positions of their genomic core region.
Sirine Abidi, Aurora Elhazaz Fernandez, Nicole Seehase, Lina Hanisch, Alexander Karlas, Volker Sandig, Ingo Jordan   +6 more
doaj   +1 more source