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The Virology of Taterapox Virus In Vitro
Viruses, 2018 Taterapox virus (TATV) is phylogenetically the closest related virus to variola—the etiological agent of smallpox. Despite the similarity, few studies have evaluated the virus.
Scott Parker +8 more
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JAMA: The Journal of the American Medical Association, 1907 In an experience with smallpox limited to the town of Colorado and occurring between the dates of April 7 and May 20, 1907, the following conditions were encountered. They are interesting as confirming previous observations as to the coincidence of variola and vaccinia.
openaire +1 more source
Remaining Questions about Clinical Variola Major
Emerging Infectious Diseases, 2011 After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
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Frontiers in Immunology, 2023 Natural killer (NK) cells have an established role in controlling poxvirus infection and there is a growing interest to exploit their capabilities in the context of poxvirus-based oncolytic therapy and vaccination.
Delphine M. Depierreux +2 more
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Advanced Science, EarlyView.Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie +24 more
wiley +1 more source
OncoImmunology, 2017 A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab.
Yuan Yuan +11 more
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Neutralization Determinants on Poxviruses
Viruses, 2023 Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
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Advanced Science, EarlyView.Primer‐programmed amplicon encoding enables reporter‐probe‐free multiplex nucleic acid identification using glass nanopore sensing and deep neural network decoding. ABSTRACT Single‐reaction multiplex nucleic acid testing (NATs) must both co‐amplify multiple targets and distinguish the resulting amplicons within the product mixture.
Md. Ahasan Ahamed +4 more
wiley +1 more source