Novel characteristics identified in two cases of feline cowpox virus infection
Journal of Feline Medicine and Surgery Open Reports, 2017 Case series summary This case series discusses novel characteristics identified in two cases of cowpox. One presented with upper airway signs, and was identified to have a focal laryngeal lesion.
Craig R Breheny +11 more
doaj +1 more source
Concomitant Human Infections with 2 Cowpox Virus Strains in Related Cases, France, 2011
Emerging Infectious Diseases, 2013 We investigated 4 related human cases of cowpox virus infection reported in France during 2011. Three patients were infected by the same strain, probably transmitted by imported pet rats, and the fourth patient was infected by another strain.
Corinne Ducournau +11 more
doaj +1 more source
Field Trial Vaccination against Cowpox in Two Alpaca Herds
Viruses, 2020 In Europe, cowpox virus (CPXV) infection in South American camelids occurs as a so-called spill-over infection. Although infected animals generally have a mild form of the disease and survive, cases of fatal generalised CPXV infection have also been ...
Almut Prkno +8 more
doaj +1 more source
Monkeypox and other orthopoxvirus zoonoses
Ветеринария сегодня, 2022 The paper highlights the current knowledge on infection biology, epidemiology and evolution of monkeypox virus (MPXV), cowpox virus (CPXV), buffalopox virus (CPXV), camelpox virus (CMLPV), as well as addresses some factors that modulate dynamics of ...
K. N. Gruzdev
doaj +1 more source
Rat-to-Human Transmission of Cowpox Infection
Emerging Infectious Diseases, 2002 We isolated Cowpox virus (CPXV) from the ulcerative eyelid lesions of a 14-year-old girl, who had cared for a clinically ill wild rat that later died. CPXV isolated from the rat (Rattus norvegicus) showed complete homology with the girl’s virus. Our case
Tom F.W. Wolfs +3 more
doaj +1 more source
Wise Blood: The Principle of Overcoming in Disease and Immunity (Part 1) [PDF]
, 2020 The immune system is an intelligently made system designed for interaction with microbes even in a perfect world; it is more than a defense. However, in a post-fall world, it is primarily a body’s defense system.
Gillen, Alan L., Huy, Keoprommony
core +1 more source
Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus [PDF]
, 1998 Recently, myxoma virus was shown to encode an additional member of the serpin superfamily. The viral gene, called serp2, was cloned, and the Serp2 protein was shown to specifically bind to interleukin-1beta (IL-1beta)-converting enzyme (ICE), thus ...
Messud-Petit, Frédérique +6 more
core
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
, 2012 Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Amy B. Pedersen +12 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]
, 2016 Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano +16 more
core +5 more sources