Results 61 to 70 of about 11,245 (224)

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Here, There, and Everywhere: The Wide Host Range and Geographic Distribution of Zoonotic Orthopoxviruses

Viruses, 2020
The global emergence of zoonotic viruses, including poxviruses, poses one of the greatest threats to human and animal health. Forty years after the eradication of smallpox, emerging zoonotic orthopoxviruses, such as monkeypox, cowpox, and vaccinia ...
Natalia Ingrid Oliveira Silva, Jaqueline Silva de Oliveira, Erna Geessien Kroon, Giliane de Souza Trindade, Betânia Paiva Drumond   +4 more
doaj   +1 more source

Relationship between food quality and body size of common vole in different habitats

Pest Management Science, EarlyView.
The body size of the common vole in crop fields (alfalfa, rape, cereals) is larger than in less‐cultivated habitats (forests, clearings, set‐aside) and is not related to food quality. Abstract BACKGROUND There is a close relationship between habitat, food and demographic parameters of common vole populations.
Eva Jánová, Ladislav Čepelka, Josef Suchomel, Marta Heroldová   +3 more
wiley   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Non-Human Primate Models of Orthopoxvirus Infections

Veterinary Sciences, 2014
Smallpox, one of the most destructive diseases, has been successfully eradicated through a worldwide vaccination campaign. Since immunization programs have been stopped, the number of people with vaccinia virus induced immunity is declining.
Anne Schmitt, Kerstin Mätz-Rensing, Franz-Josef Kaup   +2 more
doaj   +1 more source

Deliberate Extinction: Whether to Destroy the Last Smallpox Virus [PDF]

, 2004
The target problem to be examined is smallpox. Specifically, what should we (the United States and the entire world) now do with the last known residual samples of the virus that causes this uniquely horrific disease?
Koplow, David A.
core   +1 more source

Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus [PDF]

, 2008
Several species of tsetse flies can be infected by the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). Infection causes salivary gland hypertrophy and also significantly reduces the fecundity of the infected flies. To better understand the
Abd-Alla, A.M.M., Cousserans, F., Parker, A.G., Jehle, J.A., Parker, N.J., Vlak, J.M., Robinson, A.S., Bergoin, M.   +7 more
core   +2 more sources

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Dairy production practices and associated risks for bovine vaccinia exposure in cattle, Brazil

New Microbes and New Infections, 2017
A cross-sectional serosurvey was performed to identify environmental features or practices of dairy farms associated with risk for exposure to vaccinia-like viruses in dairy cattle in Brazil.
I.A. Borges, A.M. McCollum, J.M. Mehal, D. Haberling, L.A.L. Dutra, F.N. Vieira, L.A.O. Andrade, E.G. Kroon, R.C. Holman, M.G. Reynolds, G.S. Trindade   +10 more
doaj   +1 more source

Genome-wide comparison of cowpox viruses reveals a new clade related to Variola virus. [PDF]

PLoS ONE, 2013
Zoonotic infections caused by several orthopoxviruses (OPV) like monkeypox virus or vaccinia virus have a significant impact on human health. In Europe, the number of diagnosed infections with cowpox viruses (CPXV) is increasing in animals as well as in ...
Piotr Wojtek Dabrowski, Aleksandar Radonić, Andreas Kurth, Andreas Nitsche   +3 more
doaj   +1 more source