Crystal Structure of the Cowpox Virus-Encoded NKG2D Ligand OMCP [PDF]
, 2012 The NKG2D receptor is expressed on the surface of NK, T, and macrophage lineage cells and plays an important role in antiviral and antitumor immunity.
Eric Lazear +3 more
openalex +4 more sources
Monkeypox and other orthopoxvirus zoonoses
Ветеринария сегодня, 2022 The paper highlights the current knowledge on infection biology, epidemiology and evolution of monkeypox virus (MPXV), cowpox virus (CPXV), buffalopox virus (CPXV), camelpox virus (CMLPV), as well as addresses some factors that modulate dynamics of ...
K. N. Gruzdev
doaj +1 more source
Effects of nasal or pulmonary delivered treatments with an adenovirus vectored interferon (mDEF201) on respiratory and systemic infections in mice caused by cowpox and vaccinia viruses. [PDF]
PLoS ONE, 2013 An adenovirus 5 vector encoding for mouse interferon alpha, subtype 5 (mDEF201) was evaluated for efficacy against lethal cowpox (Brighton strain) and vaccinia (WR strain) virus respiratory and systemic infections in mice.
Donald F Smee +4 more
doaj +1 more source
Increasing protectivity of the smallpox vaccine
Медицинская иммунология, 2022 At the present time, vast majority of human population lacks immunity against orthopoxvirus infections caused by variola (smallpox), monkeypox, cowpox, or buffalopox viruses.
S. N. Shchelkunov +4 more
doaj +1 more source
Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
, 2011 Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone [PDF]
Antiviral Research, 2012 Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox.
Lori E. Dodd +7 more
openaire +3 more sources
Emerging and Re-Emerging Zoonoses of Dogs and Cats. [PDF]
, 2014 Since the middle of the 20th century, pets are more frequently considered as "family members" within households. However, cats and dogs still can be a source of human infection by various zoonotic pathogens.
Chomel, Bruno B
core +2 more sources
Two Distinct Clinical Courses of Human Cowpox, Germany, 2015
Viruses, 2017 Here we present two cases of human infection with cowpox virus with distinct clinical courses. A series of clinical photographs documents lesion progression over time.
Ines Eder +5 more
doaj +1 more source
Cowpox Viruses: A Zoo Full of Viral Diversity and Lurking Threats
Biomolecules, 2023 Cowpox viruses (CPXVs) exhibit the broadest known host range among the Poxviridae family and have caused lethal outbreaks in various zoo animals and pets across 12 Eurasian countries, as well as an increasing number of human cases.
Ryan C. Bruneau +2 more
doaj +1 more source
The vicious circle and infection intensity: The case of Trypanosoma microti in field vole populations [PDF]
, 2009 Objective: In natural populations, infection and condition may act synergistically to trigger a vicious circle: poor condition predisposes to host infections, which further reduce condition, and so on.
Begon, Michael +5 more
core +1 more source