The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors. [PDF]
Iyer RF +10 more
europepmc +1 more source
Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor +5 more
wiley +1 more source
Genetic diversity of feline cowpox virus, Germany 2000–2008
Recent cowpox virus (CPXV) infections of humans in Europe transmitted from cats and pet rats have risen public awareness of this rare zoonosis. Based on serosurveys wild rodents are regarded as primary reservoir hosts. Cats can become infected while hunting and could therefore serve as a sentinel for CPXV strains circulating in wild rodents.
Kaysser, Philipp +3 more
openaire +3 more sources
Why Is MS a More Frequent Complication of EBV Infection in Females?
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
An anti-poxvirus vaccine based on replicon particles of Venezuelan equine encephalitis virus (VRP) is being developed. The cowpox virus genes encoding structural proteins corresponding to vaccinia virus proteins A33, B5, and A27 were each expressed from VRP. High serum IgG titers against these proteins were generated in BALB/c mice vaccinated with each
Thornburg, Natalie J. +5 more
openaire +2 more sources
Novel Orthopoxvirus and Lethal Disease in Cat, Italy
We report detection and full-genome characterization of a novel orthopoxvirus (OPXV) responsible for a fatal infection in a cat. The virus induced skin lesions histologically characterized by leukocyte infiltration and eosinophilic cytoplasmic inclusions.
Gianvito Lanave +10 more
doaj +1 more source
Direct Priming of CD8+ T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation. [PDF]
Lin LCW +7 more
europepmc +1 more source
Structural mechanism of ER retrieval of MHC class I by cowpox.
One of the hallmarks of viral immune evasion is the capacity to disrupt major histocompatibility complex class I (MHCI) antigen presentation to evade T-cell detection.
William H McCoy +4 more
doaj +1 more source
Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. [PDF]
Shchelkunov SN +11 more
europepmc +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source

