Results 191 to 200 of about 714,188 (330)

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang   +22 more
wiley   +1 more source

COX-2 inhibition as a therapeutic strategy for bone loss in Staphylococcus aureus osteomyelitis. [PDF]

open access: yesMol Med
Chen Y   +11 more
europepmc   +1 more source

Ursodeoxycholic acid and a fluorinated analogue of 1,25 (OH)2 vitamin D3 inhibit COX-2 overex-pression in AOM-induced colonic carcinogenesis

open access: bronze, 2000
Sharad Khare   +8 more
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Targeting Biomarkers of Proliferation and Inflammation (Ki67, p53, and COX-2) in Actinic Keratoses with Photodynamic Therapy. [PDF]

open access: yesBiomedicines
Ceryn J   +8 more
europepmc   +1 more source

Cyclooxygenase-2 (COX-2) gene disruption markedly attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury

open access: bronze, 2000
Richard T. Ethridge   +4 more
openalex   +1 more source

Efficient Low‐temperature Ammonia Cracking Enabled by Strained Heterostructure Interfaces on Ru‐free Catalyst

open access: yesAdvanced Materials, EarlyView.
Leveraging the strong metal‐support interaction effect, heterostructured interfaces in a Co‐based catalyst are designed to enable low‐temperature ammonia (NH3) decomposition. The induced tensile lattice strain within the core‐shell structure modulates d‐band center of Co, enhancing NH3 adsorption and facilitating N─H bond dissociation. Furthermore, the
Pei Xiong   +10 more
wiley   +1 more source

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