Results 201 to 210 of about 755,483 (324)

Data from The mRNA Stability Factor HuR Inhibits MicroRNA-16 Targeting of COX-2

, 2023
Lisa Young, Ashleigh E. Moore, Lena Sokol, Nicole Meisner‐Kober, Dan A. Dixon   +4 more
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

A novel mode of action for COX‐2 inhibition: Targeting ATPase domain of HSP90 induces ubiquitin degradation of new client protein COX‐2

Clinical and Translational Medicine, 2022
Man Zhang, Jing Cui, Fukui Shen, Lili Ye, Chuanjing Cheng, Yang Li, Qiuyang Zhang, Lin Niu, Yuanyuan Hou, Gang Bai   +9 more
doaj   +1 more source

Presence of symptoms predicts poor survival and correlates with COX-2 expression in resected intrahepatic cholangiocarcinoma patients. [PDF]

Medicine (Baltimore)
Yang L, Wang Y, Zheng H, Pan Z, Xu Z, Wang Y, Li D, Wang Y, Yang B, Zang F, Zhang Q, Cao G, Li H, Cui Y, Wu Q, Song T, Li Q, Zhang W.   +17 more
europepmc   +1 more source

Effect of a hormone-releasing intrauterine system (Mirena®) on aromatase and Cox-2 expression in patients with adenomyosis submitted or not, to endometrial resection

, 2012
R Maia, Júlio Casoy, Clarice Haddad, Maia Jr H, Coutinho Em, N Pinheiro   +5 more
openalex   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Dual COX-2 and EGFR inhibition by pyrazole-<i>ar</i>-turmerone hybrids suppresses colorectal cancer cell proliferation. [PDF]

RSC Med Chem
Sangsawat M, Nalinratana N, Chaichompoo W, Vajragupta O, Zhu H, Song Y, Thitikornpong W, Rojsitthisak P.   +7 more
europepmc   +1 more source

Association between ABCB1, ABCG2 carrier protein and COX-2 enzyme gene polymorphisms and breast cancer risk in a Turkish population

, 2019
Kara Pala Zeliha, Dilek Öztürk Civelek, Öztaş Ezgi, Halil Kara, Uras Cihan, Gül Özhan   +5 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Reduced expression of UPF1 promotes tumor progression through stabilizing COX-2 mRNA in nasopharyngeal carcinoma. [PDF]

Front Immunol
Wu C, Xiao R, Zhang L, Chen Z, Zhang M, Li J, Zhou Y, Wang S, Jiang C, Wang H, Sun R, Mai S.   +11 more
europepmc   +1 more source