Results 221 to 230 of about 714,188 (330)

806 Lack of cross-reactivity between selective COX-2 inhibitors and aspirin (ASA) in ASA, sensitive asthmatic subjects

, 2000
Donald D. Stevenson
openalex   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Cox-2 confusion [PDF]

Genome Biology, 2003
openaire   +2 more sources

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning

Advanced Science, EarlyView.
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang, Du Cai, Junwei Liu, Zhenfeng Zhuang, Yibin Zhao, Feng‐ao Wang, Chenghang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang, Feng Gao, Xiaojian Wu   +13 more
wiley   +1 more source

Impact of Fish Oil and Flaxseed Oil on HIF-2α, COX-2 and IFN-γ Protein Expression: A Case Study in Rats With Kidney Damage Due to Circadian Rhythm Disorder. [PDF]

Vet Med Sci
Erol Z, Rugji J, Aydoğan A, Özmen Ö, Taşçı F.   +4 more
europepmc   +1 more source

Nitric Oxide Synthase/COX Cross-Talk: Nitric Oxide Activates COX-1 But Inhibits COX-2-Derived Prostaglandin Production

, 2000
Robert M. Clancy, Branko Varenika, Weiqing Huang, Les Ballou, Mukundan Attur, Ashok R. Amin, Steven B. Abramson   +6 more
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Imrecoxib attenuates osteoarthritis by modulating synovial macrophage polarization through inactivating COX-2/PGE2 signaling pathway. [PDF]

Front Bioeng Biotechnol
Peng P, Zheng W, Liu Y, Huang J, Zhang B, Shen J, Cao J.   +6 more
europepmc   +1 more source

Overlapping CRE and E‐box promoter elements can independently regulate COX‐2 gene transcription in macrophages [PDF]

, 2001
Juan Mestre, David E. Rivadeneira, Peter J. Mackrell, Michael O. Duff, Philip P. Stapleton, Vivian Mack-Strong, Sirish Maddali, Gordon K. Smyth, Tadashi Tanabe, J.M. Daly   +9 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source