Results 241 to 250 of about 714,188 (330)

Cyclooxygenase (COX)-2-derived prostaglandin D2, is an important, early, anti-inflammatory signal in experimental colitis

, 2000
Maureen N. Ajuebor, John L. Wallace
openalex   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

<i>Rosmarinus officinalis</i> L. as Fascinating Source of Potential Anticancer Agents Targeting Aromatase and COX-2: An Overview. [PDF]

Molecules
Gargano A, Greco I, Lupia C, Alcaro S, Ambrosio FA.   +4 more
europepmc   +1 more source

Expression of cyclooxygenase-2 (COX-2) in pre-neoplastic gastric mucosa

, 2000
G.V. Smith, R. Feakins, S. Patchett, M J G Farthing   +3 more
openalex   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

Investigating COX-2 and 5-LOX Enzyme-Related Anti-Inflammatory and Antioxidant Activities and Phytochemical Features of <i>Scutellaria salviifolia</i> Benth. [PDF]

Int J Mol Sci
Metkin G, Süntar İ, Şenol Deniz FS, Tugay O, Demiralp M, Pittalà V.   +5 more
europepmc   +1 more source

Mutations in P21RAS and B-catenin in azoxymethane-induced rat colonic tumors differentially regulate the ERKS, COX-2 and cyclin D1

, 2000
Marc Bissonnette, Sharad Khare, Friederike C. von Lintig, Ramesh K. Wali, Lan Nguyễn, Yingchun Zhang, John Hart, Gerry R. Boss, Thomas A. Brasitus   +8 more
openalex   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

RETRACTION: Aggravation of Alzheimer's Disease due to the COX-2-Mediated Reciprocal Regulation of IL-1β and Aβ Between Glial and Neuron Cells. [PDF]

Aging Cell
europepmc   +1 more source