Results 171 to 180 of about 1,478,952 (298)

Therapeutic effectiveness of sodium bicarbonate in diabetic ketoacidosis: A retrospective cohort analysis using the marginal structural Cox model. [PDF]

Medicine (Baltimore)
Wu X.
europepmc   +1 more source

Instrumental variable estimation of the marginal structural Cox model for time-varying treatments. [PDF]

Biometrika, 2023
Cui Y, Michael H, Tanser F, Tchetgen Tchetgen E.   +3 more
europepmc   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank. [PDF]

Biostatistics, 2022
Li R, Chang C, Justesen JM, Tanigawa Y, Qian J, Hastie T, Rivas MA, Tibshirani R.   +7 more
europepmc   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Prognostic prediction in schizophrenia using the Anderson-Gill time-dependent Cox model: a cohort study in a less-developed region of Southwest China. [PDF]

BMC Psychiatry
Tang W, Li M, Hou Z, Pu E, Cheng N, Deng L, He S, Men D, Huang J, Li Y, Wang Q, Yin J, Meng Q, Zhang T.   +13 more
europepmc   +1 more source

Adjusted Survival Curves Improve Understanding of Multivariable Cox Model Results. [PDF]

J Arthroplasty, 2021
Lundgreen CS, Larson DR, Atkinson EJ, Devick KL, Lewallen DG, Berry DJ, Maradit Kremers H, Crowson CS.   +7 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Interactive Use of Cox Model-Predicted Survival Curves: An Application Using ACS10 Score and Age to Personalize Treatment of Pediatric AML. [PDF]

JCO Precis Oncol
Selukar S, Clement H, Ni Y, Wu H, Patni T, Seffernick AE, Inaba H, Ribeiro R, Lamba J, Li Y, Pounds S.   +10 more
europepmc   +1 more source

Evaluating the effectiveness of population-based breast cancer service screening: an analysis of parsimonious patient survival information with the time-varying Cox model. [PDF]

Int J Epidemiol, 2022
Chang RW, Jen GH, Lin KC, Cheng TC, Chuang SY, Pan SL, Chen TH, Yen AM.   +7 more
europepmc   +1 more source