Results 221 to 230 of about 1,415,363 (344)

Software Application Profile: CaseCohortCoxSurvival-an R package for case-cohort inference for relative hazard and pure risk under the Cox model. [PDF]

Int J Epidemiol
Etiévant L, Gail MH.
europepmc   +1 more source

PGS1: IMPACT OF RISK MODELING INFORMATION ON THE PRESCRIBING OF COX-2 INHIBITOR AGENTS

, 2003
Linda Hoffman, Jennifer R. Pippins, MF Bullano, JJ Barron, GW Daniel, George Mayzell   +5 more
openalex   +1 more source

Cox Models: Lepeule et al. Respond [PDF]

, 2006
Johanna Lepeule, Virginie Rondeau, Jean‐François Dartigues, Laurent Filleul   +3 more
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Construction of a metabolism-malnutrition-inflammation prognostic risk score in patients with heart failure with preserved ejection fraction: a machine learning based Lasso-Cox model. [PDF]

Nutr Metab (Lond)
Feng J, Huang L, Zhao X, Li X, Xin A, Wang C, Zhang Y, Zhang J.   +7 more
europepmc   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Cox model inference for relative hazard and pure risk from stratified weight-calibrated case-cohort data. [PDF]

Lifetime Data Anal
Etievant L, Gail MH.
europepmc   +1 more source

JTE‐522, a selective COX‐2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization: A vascular cast model study

, 2004
Hirotoshi Kobayashi, Tsuyoshi Gonda, Hiroyuki Uetake, Tetsuro Higuchi, Masayuki Enomoto, Kenichi Sugihara   +5 more
openalex   +1 more source