Results 61 to 70 of about 414,671 (320)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Determining the Factors Affecting the Survival of HIV Patients: Comparison of Cox Model and the Random Survival Forest Method [PDF]
Disease and Diagnosis, 2019 Background: In recent years, sexually transmitted diseases such as AIDS have become an epidemic and are growing rapidly. Given the importance of controlling the disease in recent years, the awareness of the most important risk factors associated with ...
Nasim Karimi +5 more
doaj +1 more source
Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated [PDF]
, 2016 © 2016 Royston and Parmar. Background: Most randomized controlled trials with a time-to-event outcome are designed assuming proportional hazards (PH) of the treatment effect. The sample size calculation is based on a logrank test.
Parmar, MKB, Royston, P
core +3 more sources
Tuberculosis Research and Treatment, 2014 Introduction. Tuberculosis (TB) is a chronic infectious disease and mainly caused by mycobacterium tuberculosis (MTB). It has been one of the major causes of mortality in Ethiopia.
Kabtamu Tolosie, M. Sharma
semanticscholar +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Prognostic Factors in Patients With Colorectal Cancer at Hospital Universiti Sains Malaysia
Asian Journal of Surgery, 2010 To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia.
Anis Kausar Ghazali +3 more
doaj +1 more source
Pretreatment prognostic value of dynamic contrast-enhanced magnetic resonance imaging vascular, texture, shape, and size parameters compared with traditional survival indicators obtained from locally advanced breast cancer patients [PDF]
, 2015 Objectives: The aim of this study was to determine if associations exist between pretreatment dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI)-based metrics (vascular kinetics, texture, shape, size) and survival intervals.
Gibbs, Peter +2 more
core +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
BMC Geriatrics, 2021 Background Assessment the impact of disability on mortality among the elderly is vital to healthy ageing. The present study aimed to assess the long-term influence of disability on death in the elderly based on a longitudinal study.
Yang Yang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source