Results 61 to 70 of about 402,477 (353)

Estimation of treatment effects in weighted log-rank tests

Contemporary Clinical Trials Communications, 2017
Non-proportional hazards have been observed in clinical trials. The log-rank test loses power and the standard Cox model generally produces biased estimates under such conditions.
Ray S. Lin, Larry F. León
doaj   +1 more source

On the use of Fractional Polynomials in Dynamic Cox Models [PDF]

, 2000
Despite a sophisticated research on modelling of survival data in the last years, the most popular model used in practice is still the proportional hazards regression model proposed by Cox (1972).
Berger, Ursula, Gerein, Pia, Schäfer, Juliane, Ulm, Kurt   +3 more
core   +1 more source

Application of Cox Proportional Hazards Model in Case of Tuberculosis Patients in Selected Addis Ababa Health Centres, Ethiopia

Tuberculosis Research and Treatment, 2014
Introduction. Tuberculosis (TB) is a chronic infectious disease and mainly caused by mycobacterium tuberculosis (MTB). It has been one of the major causes of mortality in Ethiopia.
Kabtamu Tolosie, M. Sharma
semanticscholar   +1 more source

Model Regresi Cox Proportional Hazards Pada Data Lama Studi Mahasiswa (Studi Kasus Di Fakultas Sains Dan Matematika Universitas Diponegoro Semarang Mahasiswa Angkatan 2009) [PDF]

, 2014
High education has important role to increase the intellectual life of the nation and the development of natural sciences and technology by producing the quality graduates. The quality graduates just need 48 month to finish the study.
Hutahaean, L. P. (Landong), Mukid, M. A. (Moch), Wuryandari, T. (Triastuti)   +2 more
core  

Multiple imputation in Cox regression when there are time-varying effects of covariates. [PDF]

, 2017
In Cox regression, it is important to test the proportional hazards assumption and sometimes of interest in itself to study time-varying effects (TVEs) of covariates. TVEs can be investigated with log hazard ratios modelled as a function of time. Missing
Abrahamowicz, Abrahamowicz, Bartlett, Bartlett, Bartlett, Berger, Binquet, Borgan, Breslow, Buchholz, Carpenter, Collett, Collins, Cox, Cox, Cummins, Durrleman, Ford, Gerds, Gore, Grambsch, Gray, Hastie, Heinzl, Hess, Kooperberg, Li, Liu, Meng, Moreau, Morris, Ng'andu, Quantin, Royston, Royston, Rubin, Sauerbrei, Sauerbrei, Scheike, Schemper, Schoenfeld, Seaman, Stone, Therneau, Tian, Van Buuren, Van Buuren, Verweij, White, White, Winnett, Wood, Wynant, Yan, Zucker   +54 more
core   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Estimation in Cox proportional hazards model with heteroscedastic errors in covariates

Modern Stochastics: Theory and Applications
Consistent estimators of the baseline hazard rate and the regression parameter are constructed in the Cox proportional hazards model with heteroscedastic measurement errors, assuming that the baseline hazard function belongs to a certain class of ...
Oksana Chernova
doaj   +1 more source

A Resampling Method to Improve the Prognostic Model of End-Stage Kidney Disease: A Better Strategy for Imbalanced Data

Frontiers in Medicine, 2022
BackgroundPrognostic models can help to identify patients at risk for end-stage kidney disease (ESKD) at an earlier stage to provide preventive medical interventions. Previous studies mostly applied the Cox proportional hazards model.
Xi Shi, Xi Shi, Tingyu Qu, Gijs Van Pottelbergh, Marjan van den Akker, Marjan van den Akker, Bart De Moor   +6 more
doaj   +1 more source

joineR: Joint modelling of repeated measurements and time-to-event data [PDF]

, 2012
The joineR package implements methods for analysing data from longitudinal studies in which the response from each subject consists of a time-sequence of repeated measurements and a possibly censored time-toevent outcome.
Diggle, Peter, Henderson, Robin, Kolamunnage-Dona, Ruwanthi, Philipson, Pete, Sousa, Ines, Williamson, Paula   +5 more
core