Results 1 to 10 of about 43,538 (254)
Magnetic Resonance Imaging Features of Pediatric Coxsackievirus Encephalitis
Journal of the Belgian Society of Radiology, 2019 Coxsackievirus, a common pathogen causing pediatric infection, typically causes a mild, nonspecific illness with low-grade fever, but can cause severe illness on rare occasions.
Yang-Kai Fan, Yu-Peng Liu
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PLoS Pathogens, 2018 Cathepsin B (CatB) is a cysteine proteolytic enzyme widely expressed in various cells and mainly located in the lysosomes. It contributes to the pathogenesis and development of many diseases. However, the role of CatB in viral myocarditis (VMC) has never
Yaping Wang +8 more
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Antiviral Effects of Menthol on Coxsackievirus B
Viruses, 2020 Coxsackievirus B (CVB) is a common human enterovirus that causes systemic infection but specifically replicates to high titers in the pancreas. It was reported that certain viruses induce mitochondrial fission to support infection. We documented that CVB
David J.R. Taylor +10 more
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Coxsackievirus and type 1 diabetes: diabetogenic mechanisms and implications for prevention.
Endocrine reviews, 2023 The evidence for an association between Coxsackievirus B (CVB) infection, pancreatic islet autoimmunity and clinical type 1 diabetes is increasing. Results from prospective cohorts and pancreas histopathology studies have provided a compelling case ...
A. Carré +4 more
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Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus
Nature Reviews Endocrinology, 2022 Enteroviruses are believed to trigger or accelerate islet autoimmunity in genetically susceptible individuals, thereby resulting in loss of functional insulin-producing β-cells and type 1 diabetes mellitus (T1DM).
M. Nekoua, E. K. Alidjinou, D. Hober
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Enteroviral infections are not associated with type 2 diabetes
Frontiers in Endocrinology, 2023 IntroductionFor more than a century, enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly presented during childhood highly correlate with autoimmunity and T1D.
Huan Liu +11 more
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Coxsackievirus B3 targets TFEB to disrupt lysosomal function
Autophagy, 2021 Coxsackievirus B3 (CVB3) is a prevalent etiological agent for viral myocarditis and neurological disorders, particularly in infants and young children. Virus-encoded proteinases have emerged as cytopathic factors that contribute to disease pathogenesis ...
Y. Mohamud +6 more
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Coxsackievirus B3—Its Potential as an Oncolytic Virus
Viruses, 2021 Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise untreatable types of cancer. Despite encouraging developments in recent years, the limited fraction of patients responding to therapy has demonstrated the need to ...
Anja Geisler +4 more
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Frontiers in Chemistry, 2021 Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba +10 more
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Specific Bacterial Cell Wall Components Influence the Stability of Coxsackievirus B3
bioRxiv, 2021 Previous data indicate that several enteric viruses utilize bacteria to promote intestinal infection and viral stability. Here, we show that specific bacteria and bacterial cell wall components are required to enhance infectivity and stability of ...
Adeeba H. Dhalech +2 more
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