Results 1 to 10 of about 31,795 (209)
Does Coxsackievirus B3 Require Autophagosome Formation for Replication? Evidence for an Autophagosome-Independent Mechanism: Insights into Its Limited Potential as a Therapeutic Target [PDF]
PharmaceuticalsBackground/Objectives: Coxsackievirus B3 (CVB3), a neurotropic enterovirus, is a major causative agent of viral encephalitis and myocarditis, yet no protective vaccine or effective antiviral therapy is currently available.
Yun Ji Ga, Jung-Yong Yeh
doaj +2 more sources
Enteroviral infections are not associated with type 2 diabetes
Frontiers in Endocrinology, 2023 IntroductionFor more than a century, enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly presented during childhood highly correlate with autoimmunity and T1D.
Huan Liu +11 more
doaj +1 more source
Frontiers in Chemistry, 2021 Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba +10 more
doaj +1 more source
Development of antiviral therapeutics combating coxsackievirus type B3 infection
Инфекция и иммунитет, 2021 Enteroviruses comprise highly diverse group of single-stranded positive RNA viruses belonging to Enterovirus genus, Picornaviridae family. They are the most prevalent viruses worldwide highlighted by high resistance to environmental cues.
A. S. Volobueva +2 more
doaj +1 more source
Viruses, 2021 Genetic screens using CRISPR/Cas9 have been exploited to discover host–virus interactions. These screens have identified viral dependencies on host proteins during their life cycle and potential antiviral strategies.
Hye Jin Shin +7 more
doaj +1 more source
ASSOCIATION OF ANTI-COXSACKIE VIRUS-B IgG WITH AUTOANTIBODIES RELATED TO TYPE 1 DIABETES MELLITUS
The Iraqi Journal of Medical Sciences, 2022 Background: Coxsackievirus B is a virus may cause type 1 diabetes. There are links between Coxsackievirus B infections and type 1 diabetes. The presence of autoantibodies in pancreatic beta cells has been linked to the development of type 1 ...
Hakeem Gh. Hassan +2 more
doaj +1 more source
Cells, 2021 Chronic stimulation by infectious pathogens or self-antigen glucosylsphingosine (GlcSph) can lead to monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM).
Jean Harb +14 more
doaj +1 more source
Viruses, 2022 TRIM7 catalyzes the ubiquitination of multiple substrates with unrelated biological functions. This cross-reactivity is at odds with the specificity usually displayed by enzymes, including ubiquitin ligases.
Jakub Luptak +8 more
doaj +1 more source
Virus Infection Is an Instigator of Intestinal Dysbiosis Leading to Type 1 Diabetes
Frontiers in Immunology, 2021 In addition to genetic predisposition, environmental determinants contribute to a complex etiology leading to onset of type 1 diabetes (T1D). Multiple studies have established the gut as an important site for immune modulation that can directly impact ...
Zachary J. Morse, Marc S. Horwitz
doaj +1 more source
Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010–2016
Emerging Infectious Diseases, 2018 Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015.
Yu Li +16 more
doaj +1 more source