Magnetic Resonance Imaging Features of Pediatric Coxsackievirus Encephalitis
Journal of the Belgian Society of Radiology, 2019 Coxsackievirus, a common pathogen causing pediatric infection, typically causes a mild, nonspecific illness with low-grade fever, but can cause severe illness on rare occasions.
Yang-Kai Fan, Yu-Peng Liu
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Antiviral Effects of Menthol on Coxsackievirus B
Viruses, 2020 Coxsackievirus B (CVB) is a common human enterovirus that causes systemic infection but specifically replicates to high titers in the pancreas. It was reported that certain viruses induce mitochondrial fission to support infection. We documented that CVB
David J.R. Taylor +10 more
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A novel microRNA promotes coxsackievirus B4 infection of pancreatic β cells [PDF]
Frontiers in ImmunologyThe epidemiological association of coxsackievirus B infection with type 1 diabetes suggests that therapeutic strategies that reduce viral load could delay or prevent disease onset.
Salima Lalani +7 more
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Clinical and Genomic Epidemiology of Coxsackievirus A21 and Enterovirus D68 in Homeless Shelters, King County, Washington, USA, 2019–2021 [PDF]
Emerging Infectious DiseasesCongregate homeless shelters are disproportionately affected by infectious disease outbreaks. We describe enterovirus epidemiology across 23 adult and family shelters in King County, Washington, USA, during October 2019–May 2021, by using repeated cross-
Sarah N. Cox +22 more
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In Vivo and In Vitro Studies Assessing the Antiviral Efficacy of Double Combinations Against Coxsackievirus B Infection [PDF]
MicroorganismsCoxsackievirus B (CVB) infections, ranging from mild to severe diseases, lack specific antiviral treatments, underscoring the need for novel therapeutic strategies.
Adelina Stoyanova +3 more
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Frontiers in Chemistry, 2021 Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba +10 more
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Coxsackievirus and type 1 diabetes: diabetogenic mechanisms and implications for prevention.
Endocrine reviews, 2023 The evidence for an association between Coxsackievirus B (CVB) infection, pancreatic islet autoimmunity and clinical type 1 diabetes is increasing. Results from prospective cohorts and pancreas histopathology studies have provided a compelling case ...
A. Carré +4 more
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Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus
Nature Reviews Endocrinology, 2022 Enteroviruses are believed to trigger or accelerate islet autoimmunity in genetically susceptible individuals, thereby resulting in loss of functional insulin-producing β-cells and type 1 diabetes mellitus (T1DM).
M. P. Nekoua, E. K. Alidjinou, D. Hober
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Development of antiviral therapeutics combating coxsackievirus type B3 infection
Инфекция и иммунитет, 2021 Enteroviruses comprise highly diverse group of single-stranded positive RNA viruses belonging to Enterovirus genus, Picornaviridae family. They are the most prevalent viruses worldwide highlighted by high resistance to environmental cues.
A. S. Volobueva +2 more
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Coxsackievirus B3 targets TFEB to disrupt lysosomal function
Autophagy, 2021 Coxsackievirus B3 (CVB3) is a prevalent etiological agent for viral myocarditis and neurological disorders, particularly in infants and young children. Virus-encoded proteinases have emerged as cytopathic factors that contribute to disease pathogenesis ...
Y. Mohamud +6 more
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