Magnetic Resonance Imaging Features of Pediatric Coxsackievirus Encephalitis
Journal of the Belgian Society of Radiology, 2019 Coxsackievirus, a common pathogen causing pediatric infection, typically causes a mild, nonspecific illness with low-grade fever, but can cause severe illness on rare occasions.
Yang-Kai Fan, Yu-Peng Liu
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Does Coxsackievirus B3 Require Autophagosome Formation for Replication? Evidence for an Autophagosome-Independent Mechanism: Insights into Its Limited Potential as a Therapeutic Target [PDF]
PharmaceuticalsBackground/Objectives: Coxsackievirus B3 (CVB3), a neurotropic enterovirus, is a major causative agent of viral encephalitis and myocarditis, yet no protective vaccine or effective antiviral therapy is currently available.
Yun Ji Ga, Jung-Yong Yeh
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PLoS Pathogens, 2018 Cathepsin B (CatB) is a cysteine proteolytic enzyme widely expressed in various cells and mainly located in the lysosomes. It contributes to the pathogenesis and development of many diseases. However, the role of CatB in viral myocarditis (VMC) has never
Yaping Wang +8 more
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Antiviral Effects of Menthol on Coxsackievirus B
Viruses, 2020 Coxsackievirus B (CVB) is a common human enterovirus that causes systemic infection but specifically replicates to high titers in the pancreas. It was reported that certain viruses induce mitochondrial fission to support infection. We documented that CVB
David J.R. Taylor +10 more
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Early Treatment of Coxsackievirus B3–Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy [PDF]
Circulation: Heart Failure, 2019 Background: Coxsackie-B-viruses (CVB) are frequent causes of acute myocarditis and dilated cardiomyopathy, but an effective antiviral therapy is still not available. Previously, we and others have demonstrated that treatment with an engineered sCAR-Fc (soluble coxsackievirus-adenovirus receptor fused to the carboxyl-terminus of
Sandra, Pinkert +10 more
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Enteroviral infections are not associated with type 2 diabetes
Frontiers in Endocrinology, 2023 IntroductionFor more than a century, enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly presented during childhood highly correlate with autoimmunity and T1D.
Huan Liu +11 more
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Coxsackievirus and type 1 diabetes: diabetogenic mechanisms and implications for prevention.
Endocrine reviews, 2023 The evidence for an association between Coxsackievirus B (CVB) infection, pancreatic islet autoimmunity and clinical type 1 diabetes is increasing. Results from prospective cohorts and pancreas histopathology studies have provided a compelling case ...
A. Carré +4 more
semanticscholar +1 more source
Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus
Nature Reviews Endocrinology, 2022 Enteroviruses are believed to trigger or accelerate islet autoimmunity in genetically susceptible individuals, thereby resulting in loss of functional insulin-producing β-cells and type 1 diabetes mellitus (T1DM).
M. Nekoua, E. K. Alidjinou, D. Hober
semanticscholar +1 more source
Development of antiviral therapeutics combating coxsackievirus type B3 infection
Инфекция и иммунитет, 2021 Enteroviruses comprise highly diverse group of single-stranded positive RNA viruses belonging to Enterovirus genus, Picornaviridae family. They are the most prevalent viruses worldwide highlighted by high resistance to environmental cues.
A. S. Volobueva +2 more
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