Results 11 to 20 of about 22,089 (224)
Suppression of Calcium Influx Reduces Coxsackievirus B3 Lethality With Elevated Interferon Beta Responses in Mice. [PDF]
J Med VirolABSTRACT The disease course of severe enterovirus (EV) infection with hepatic necrosis is usually fulminant and fatal. Coxsackievirus (CVB3) is the emerging and important serotype of newborn EV inducing hepatic necrosis. Calcium (Ca2+) regulates host immunity, type I interferon (IFN‐I), and viral infections.
Hsiao YL, Hung CH, Yeh MT, Chen SH.
europepmc +2 more sources
Current Research in Microbial Sciences, 2023 Infection with coxsackievirus A10 (CV-A10) can cause hand-foot-mouth disease and is also associated with severe complications, including viral pneumonia, aseptic and viral meningitis.
Yongkang Chen +8 more
doaj +2 more sources
Replicase gene of coxsackievirus B3
Journal of Virology, 1984 A cDNA copy covering two-thirds of the coxsackievirus B3 genome was cloned in the PstI site of the pBR322 vector. A nucleotide sequence containing the gene for the viral replicase and the 3' noncoding region of the coxsackievirus B3 genome was determined.
P O, Stålhandske +2 more
openaire +3 more sources
Does Coxsackievirus B3 Require Autophagosome Formation for Replication? Evidence for an Autophagosome-Independent Mechanism: Insights into Its Limited Potential as a Therapeutic Target [PDF]
PharmaceuticalsBackground/Objectives: Coxsackievirus B3 (CVB3), a neurotropic enterovirus, is a major causative agent of viral encephalitis and myocarditis, yet no protective vaccine or effective antiviral therapy is currently available.
Yun Ji Ga, Jung-Yong Yeh
doaj +2 more sources
Antigenic Sites of Coxsackievirus A9
Virology, 1998 Antigenic analysis of coxsackievirus A9 (CAV9) was carried out by using a peptide scanning method. Immunogenic regions in the capsid proteins VP1, VP2, and VP3 were recognized by antibodies in the sera of virus-immunized rabbits. The peptide sequences were scanned using a 12-amino-acid window and three-residue shift.
Pulli, Timo +3 more
openaire +3 more sources
The Antibiotic Neomycin Enhances Coxsackievirus Plaque Formation
mSphere, 2019 Coxsackievirus typically infects humans via the gastrointestinal tract, which has a large number of microorganisms collectively referred to as the microbiota.
Mikal A. Woods Acevedo +2 more
doaj +2 more sources
ASSOCIATION OF ANTI-COXSACKIE VIRUS-B IgG WITH AUTOANTIBODIES RELATED TO TYPE 1 DIABETES MELLITUS
The Iraqi Journal of Medical Sciences, 2022 Background: Coxsackievirus B is a virus may cause type 1 diabetes. There are links between Coxsackievirus B infections and type 1 diabetes. The presence of autoantibodies in pancreatic beta cells has been linked to the development of type 1 ...
Hakeem Gh. Hassan +2 more
doaj +9 more sources
Enteroviral infections are not associated with type 2 diabetes
Frontiers in Endocrinology, 2023 IntroductionFor more than a century, enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly presented during childhood highly correlate with autoimmunity and T1D.
Huan Liu +11 more
doaj +1 more source
Frontiers in Chemistry, 2021 Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba +10 more
doaj +1 more source