Virus induced dysbiosis promotes type 1 diabetes onset
Frontiers in Immunology, 2023 Autoimmune disorders are complex diseases of unclear etiology, although evidence suggests that the convergence of genetic susceptibility and environmental factors are critical.
Zachary J. Morse +6 more
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A transcriptomic investigation of handicap models in sexual selection [PDF]
, 2014 We are grateful to D. Calder and T. Helps for access to study sites, and G. Murray-Dickson and M. Oliver for help with fieldwork and comments on manuscript drafts. This work was funded by NERC grant NE/D000602/1 (SBP), a NERC advanced fellowship (FM) and
Martinez-Padilla, Jesus +5 more
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CALCOCO2/NDP52 and SQSTM1/p62 differentially regulate coxsackievirus B3 propagation
Cell Death and Differentiation, 2018 Cell autonomous immunity is the ability of individual cells to initiate a first line of host defense against invading microbes, such as viruses. Autophagy receptors, a diverse family of multivalent proteins, play a key role in this host response by ...
Y. Mohamud +5 more
semanticscholar +1 more source
A battle between host and pathogen : the innate immune response and enterovirus evasion strategies [PDF]
, 2014 Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and ...
Lind, Katharina
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Emerging Coxsackievirus A6 Causing Hand, Foot and Mouth Disease, Vietnam
Emerging Infectious Diseases, 2018 Hand, foot and mouth disease (HFMD) is a major public health issue in Asia and has global pandemic potential. Coxsackievirus A6 (CV-A6) was detected in 514/2,230 (23%) of HFMD patients admitted to 3 major hospitals in southern Vietnam during 2011–2015 ...
N. T. Anh +24 more
semanticscholar +1 more source
Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
, 2013 <p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo +47 more
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Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy [PDF]
, 2018 Inflammation in myocarditis induces cardiac injury and triggers disease progression to heart failure. NLRP3 inflammasome activation is a newly identified amplifying step in the pathogenesis of myocarditis.
A Abbate +43 more
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Circulating Coxsackievirus A16 Identified as Recombinant Type A Human Enterovirus, China
Emerging Infectious Diseases, 2011 To determine the relationship of coxsackievirus A16 (CA16) to prototype CA16-G10, we conducted a phylogenetic analysis of circulating CA16 strains in China.
Ke Zhao +5 more
doaj +1 more source
Viruses associated with pneumonia in adults. [PDF]
, 2012 Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
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Journal of Medical Case Reports, 2019 BackgroundFulminant type 1 diabetes is characterized by an intrinsic insulin deficiency resulting from the severe destruction of pancreatic β cells and it rapidly leads to ketoacidosis.
T. Hayakawa +8 more
semanticscholar +1 more source