Results 61 to 70 of about 24,234 (207)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Enteroviruses and T1D: Is It the Virus, the Genes or Both which Cause T1D

open access: yesMicroorganisms, 2020
Type 1 diabetes (T1D) is a chronic autoimmune disorder that results from the selective destruction of insulin-producing β-cells in the pancreas. Up to now, the mechanisms triggering the initiation and progression of the disease are, in their complexity ...
Shirin Geravandi   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Serologic prevalence of coxsackievirus group B in Greece

open access: yes, 2007
Coxsackieviruses are human enteroviruses, which have been associated with myocarditis/pericarditis and sudden death. In one investigation (Spanakis N, Manolis EN, Tsakris A, Tsiodras S, Panagiotopoulos T, Saroglou G, and Legakis NJ: J Clin Pathol 2005;58:
Foundouli, K.   +10 more
core   +2 more sources

Trends in the enterovirus surveillance in Oslo, Norway before and during the COVID-19 pandemic

open access: yesFrontiers in Virology
BackgroundEnteroviruses have the potential to cause both high morbidity and mortality especially in children. High season in Norway is between August and November, but this seasonality was interrupted by the COVID-19 pandemic.MethodsIn this study, we ...
Susanne Dudman   +10 more
doaj   +1 more source

Epidemics of enterovirus infection in Chungnam Korea, 2008 and 2009

open access: yesVirology Journal, 2011
Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009.
Hwang SeoYeon   +11 more
doaj   +1 more source

Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells

open access: yesViruses, 2020
Enteroviruses manipulate host membranes to form replication organelles, which concentrate viral and host factors to allow for efficient replication. However, this process has not been well-studied in living cells throughout the course of infection.
Nicholas J. Lennemann   +2 more
doaj   +1 more source

Refining a preclinical model of viral myocarditis in accordance with biotech standards

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 9, Page 1712-1728, September 2026.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen   +9 more
wiley   +1 more source

Applications of coxsackievirus A21 in oncology

open access: yesOncolytic Virotherapy, 2014
The clinical management of cancer continues to be dominated by macroscopic surgical resection, radiotherapy, and cytotoxic drugs. The major challenge facing oncology is to achieve more selective, less toxic and effective methods of targeting disseminated tumors, a challenge oncolytic virotherapy may be well-placed to meet.
Bradley, S   +5 more
openaire   +5 more sources

Molecular epidemiology of Coxsackievirus B3

open access: yesInfection, Genetics and Evolution, 2010
Molecular epidemiological characteristics are needed to understand the impact of Coxsackievirus B3 (CV-B3) infection, since no CV-B3 genotyping literature is available. Twenty-nine CV-B3 Taiwan strains obtained from 1992 to 2005 were analyzed. A phylogenetic tree was constructed based on the 290 nucleotide sequence of the VP1 gene of Taiwan isolates ...
Pei-Yu, Chu   +11 more
openaire   +2 more sources

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