Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini +4 more
wiley +1 more source
Coxsackievirus B3 Replication and Pathogenesis
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites. Indeed, they must cleverly exploit various compartments of host cells to complete their life cycle, and consequently launch disease. Evolution has equipped this pico-rna-virus, CVB3, to use different strategies, including CVB3-induced direct damage to host cells ...
Farshid S, Garmaroudi +7 more
openaire +2 more sources
The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis
The host response to Coxsackievirus infection is complex, including T lymphocytes, B lymphocytes, natural killer cells, and macrophages. Although Coxsackievirus infection induces expression of inducible nitric oxide synthase (NOS2; EC 1.14.13.39) in ...
Moncada, Salvador +17 more
core +1 more source
Modern Approaches to Enterovirus-Based Oncolytic Immune Virotherapy of Malignant Diseases
The aim. The review presents the analysis of publications on modern approaches to oncolytic viral immunotherapy of malignant diseases which is predominantly based on usage of enteroviruses.Materials and methods.
E. R. Nemtsova, E. A. Plotnikova
doaj +1 more source
Coxsackievirus B3, Shandong Province, China, 1990–2010
To determine the cause of a 2008 outbreak of aseptic meningitis in Shandong Province, China, we analyzed samples from outbreak patients and coxsackievirus B3 samples collected during 1990–2010 surveillance. The cause of the outbreak was coxsackievirus B3,
Zexin Tao +9 more
doaj +1 more source
Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple +30 more
wiley +1 more source
MOPS and coxsackievirus B3 stability
Study of coxsackievirus B3 strain 28 (CVB3/28) stability using MOPS to improve buffering in the experimental medium revealed that MOPS (3-morpholinopropane-1-sulfonic acid) increased CVB3 stability and the effect was concentration dependent. Over the pH range 7.0-7.5, virus stability was affected by both pH and MOPS concentration.
Steven D, Carson +2 more
openaire +2 more sources
Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation
In this study, we characterized the role of host cell protein tyrosyl-DNA phosphodiesterase 2 (TDP2) activity, also known as VPg unlinkase, in picornavirus infections in a human cell model of infection.
Autumn C. Holmes +3 more
doaj +1 more source
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source
Coxsackievirus and Adenovirus Receptor Cytoplasmic and Transmembrane Domains Are Not Essential for Coxsackievirus and Adenovirus Infection [PDF]
ABSTRACTCoxsackievirus and adenovirus receptor (CAR) from which the cytoplasmic domain had been deleted and glycosylphosphatidylinositol (GPI)-anchored CAR lacking both transmembrane and cytoplasmic domains were both capable of facilitating adenovirus 5-mediated gene delivery and infection by coxsackievirus B3.
X, Wang, J M, Bergelson
openaire +2 more sources

