Results 61 to 70 of about 40,540 (250)

Treatability of U.S. Environmental Protection Agency Contaminant Candidate List Viruses: Removal of Coxsackievirus and Echovirus using Enhanced Coagulation [PDF]

, 2008
Enhanced coagulation was evaluated for removal efficacy of coxsackievirus and echovirus (Contaminant Candidate List [CCL] enteroviruses), poliovirus, four potential surrogate bacteriophages, and dissolved organic carbon (DOC).
Abbaszadegan, Morteza, Mayer, Brooke, Ryu, Hodon   +2 more
core   +1 more source

Atypical forms of hand, foot, and mouth disease: our experience [PDF]

, 2014
Introduzione: La malattia mani-piedi-bocca è una patologia infettiva tipica della prima infanzia causata dagli enterovirus, in particolare i sierotipi Coxsackievirus A16 ed Enterovirus 71.
Dondi, Arianna <1979>
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier

mSphere, 2017
The blood-brain barrier (BBB) comprises the foremost protective barrier in the brain and is composed in part of a layer of microvascular endothelial cells that line the capillaries surrounding the brain.
John C. Bramley, Coyne G. Drummond, Nicholas J. Lennemann, Charles A. Good, Kwang Sik Kim, Carolyn B. Coyne   +5 more
doaj   +1 more source

Fulminant type 1 diabetes mellitus associated with Coxsackievirus type B1 infection during pregnancy: a case report

Journal of Medical Case Reports, 2019
BackgroundFulminant type 1 diabetes is characterized by an intrinsic insulin deficiency resulting from the severe destruction of pancreatic β cells and it rapidly leads to ketoacidosis.
T. Hayakawa, Yoshio Nakano, Kana Hayakawa, Hiroaki Yoshimatu, Yoshikazu Hori, Kazuki Yamanishi, Hirofumi Yamanishi, T. Ota, Tokuzo Fujimoto   +8 more
semanticscholar   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

High‐Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15‐Specific Protease mUSP18

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
Deubiquitinases (DUBs) and Ub‐like proteases are attractive but challenging drug targets. We developed a high‐throughput synthesis method and prepared a 7536‐member cyanimide DUB‐targeted compound library in 1536‐well plates, using Echo acoustic dispensing. Screening yielded a selective, 35 nM inhibitor of mUSP18, the main ISG15 protease.
Raymond Kooij, Vito Pol, Jin Gan, Bjorn R. van Doodewaerd, Aysegul Sapmaz, Marta Campos Alonso, Günter Fritz, Klaus‐Peter Knobeloch, Paul P. Geurink   +8 more
wiley   +2 more sources

IRES-dependent translational control during virus-induced endoplasmic reticulum stress and apoptosis

Frontiers in Microbiology, 2012
Many virus infections and stresses can induce endoplasmic reticulum (ER) stress response, a host self defense mechanism against viral invasion and stress.
Paul eHanson, Huifang M. Zhang, Maged Gomma Hemida, Xin eYe, Ye eQiu, Decheng eYang   +5 more
doaj   +1 more source

MOPS and coxsackievirus B3 stability

Virology, 2017
Study of coxsackievirus B3 strain 28 (CVB3/28) stability using MOPS to improve buffering in the experimental medium revealed that MOPS (3-morpholinopropane-1-sulfonic acid) increased CVB3 stability and the effect was concentration dependent. Over the pH range 7.0-7.5, virus stability was affected by both pH and MOPS concentration.
Steven D, Carson, Susan, Hafenstein, Hyunwook, Lee   +2 more
openaire   +2 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source