Results 71 to 80 of about 40,540 (250)

Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating

open access: yesNature Communications, 2018
Coxsackievirus A10 (CVA10), a human type-A Enterovirus (HEV-A), can cause diseases ranging from hand-foot-and-mouth disease to polio-myelitis-like disease.
Ling Zhu   +9 more
semanticscholar   +1 more source

Human picornaviruses associated with neurological diseases and their neutralization by antibodies [PDF]

open access: yes, 2017
Picornaviruses are the most commonly encountered infectious agents in mankind. They typically cause mild infections of the gastrointestinal or respiratory tract, but sometimes also invade the central nervous system.
Ang   +22 more
core   +1 more source

Coxsackievirus B3 Replication and Pathogenesis

open access: yesFuture Microbiology, 2015
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites. Indeed, they must cleverly exploit various compartments of host cells to complete their life cycle, and consequently launch disease. Evolution has equipped this pico-rna-virus, CVB3, to use different strategies, including CVB3-induced direct damage to host cells ...
Farshid S, Garmaroudi   +7 more
openaire   +2 more sources

Molecular Phylogeny of Coxsackievirus A16 [PDF]

open access: yesJournal of Clinical Microbiology, 2014
We have read the article by [Zong et al.][1] with considerable interest ([1][2]). They described the molecular phylogeny of Coxsackievirus A16 (CVA16) in Shenzhen, China, from 2005 to 2009. In their paper, they claimed that “Subtype B2 could be further divided into clusters B2a, B2b, and B2c ...
Ting, Sun   +3 more
openaire   +2 more sources

Neoadjuvant therapy in skin cancer: current evidence and future perspectives

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello   +2 more
wiley   +1 more source

Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways

open access: yesViruses, 2016
To successfully replicate, viruses protect their genomic material from degradation by the host cell. RNA viruses must contend with numerous destabilizing host cell processes including mRNA decay pathways and viral RNA (vRNA) degradation resulting from ...
Wendy Ullmer, Bert L. Semler
doaj   +1 more source

Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation

open access: yesViruses, 2020
In this study, we characterized the role of host cell protein tyrosyl-DNA phosphodiesterase 2 (TDP2) activity, also known as VPg unlinkase, in picornavirus infections in a human cell model of infection.
Autumn C. Holmes   +3 more
doaj   +1 more source

Reflectance confocal microscopy for the diagnosis of skin infections and infestations [PDF]

open access: yes, 2020
Reflectance confocal microscopy (RCM) is a noninvasive real-time imaging technique that has been widely used for the diagnosis of skin cancer. More recently, it has been reported as a useful tool for the diagnosis and management of several inflammatory ...
Arzberger, Edith   +6 more
core  

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy [PDF]

open access: yes, 2018
Inflammation in myocarditis induces cardiac injury and triggers disease progression to heart failure. NLRP3 inflammasome activation is a newly identified amplifying step in the pathogenesis of myocarditis.
A Abbate   +43 more
core   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte   +2 more
wiley   +1 more source

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