Results 101 to 110 of about 1,351 (168)

Innate Immunity: TOLL-LIKE RECEPTORS, NF-κB ACTIVATION, AND COXSACKIEVIRUS

, 2005
The purpose of this project was to determine whether the Coxsackievirus B (CVB) uses toll-like receptors (TLR) to enter cells. In the signal transduction pathway of Toll-like Receptors, phosphorylation of the inhibitor protein IkB (by either of the IkB ...
Dobson, Jason R.
core  

Limited proteolysis of the coxsackievirus and adenovirus receptor (CAR) on HeLa cells exposed to trypsin

, 2000
Trypsin treatment of HeLa cells results in a limited proteolysis of the coxsackievirus and adenovirus receptor (CAR) after which the cleaved CAR remains cell-associated and tryptic peptides remain associated through disulfide bonds.
Carson, Steven D., Steven D. Carson
core   +1 more source

The Pathogenesis and Virulence of the Major Enterovirus Pathogens Associated with Severe Clinical Manifestations: A Comprehensive Review

Cells
Enteroviruses (EVs), particularly those within the species Enterovirus A and B, represent a significant global public health burden, especially in infants and young children. While often causing self-limiting hand, foot, and mouth disease (HFMD), certain
Yuwei Liu, Maiheliya Maisimu, Zhihang Ge, Suling Xiao, Haoran Wang   +4 more
doaj   +1 more source

Maternal Coxsackievirus B Induced Dysregulation of SUMOylation Processes as a Potential Cause of Hypoplastic Left Heart Syndrome

, 2018
Hypoplastic Left Heart Syndrome (HLHS) is a life-threatening congenital heart defect with unknown etiology. Here we hypothesize that HLHS has etiologic roots in maternal asymptomatic coxsackievirus B infection.
Severson, Sarah, Kemp, Bailey
core  

Virus-Induced Abl and Fyn Kinase Signals Permit Coxsackievirus Entry through Epithelial Tight Junctions

, 2006
SummaryGroup B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the mechanism by which this occurs remains uncertain.
Bergelson, Jeffrey M., Coyne, Carolyn B., Carolyn B. Coyne, Jeffrey M. Bergelson   +3 more
core   +1 more source

Interaction with Coxsackievirus and Adenovirus Receptor, but Not with Decay-Accelerating Factor (DAF), Induces A-Particle Formation in a DAF-Binding Coxsackievirus B3 Isolate

, 2004
Although many coxsackie B viruses interact with decay accelerating factor (DAF), attachment to DAF by itself is not sufficient to initiate infection.
J. Charles Whitbeck, Jeffrey M. Bergelson   +1 more
core  

Echovirus 30 and coxsackievirus A9 infection among young neonates with sepsis in Iran

Iranian Journal of Microbiology, 2018
Background and Objectives: Human enteroviruses (EV) are the most common causes of neonatal sepsis-like disease. The frequencies of EV including coxsackievirus A, coxsackievirus B and Echovirus serotypes have been studied in young infants (younger than ...
Abdolnabi Shabani, Manoochehr Makvandi, Alireza Samarbafzadeh, Ali Teimoori, Mojtaba Rasti, Chiman Karami, Nasteran Rastegarvand, Roya Nikfar, Ahmad Shamsizadeh, Azam Salehi, Kambiz Ahmadi Angali   +10 more
doaj  

Research progress and application prospects of animal models of group B Coxsackievirus infections

Emerging Microbes and Infections
Group B Coxsackieviruses (CVBs) consist of six serotypes, CVB1 to CVB6, which can clinically affect the heart, brain, liver, pancreas and other organs, causing myocarditis, encephalitis, myelitis, pancreatitis, hand-foot-and-mouth disease (HFMD) and ...
Shihan Weng, Rui Zhu, Yuanyuan Wu, Ningshao Xia, Longfa Xu, Tong Cheng   +5 more
doaj   +1 more source

Coxsackievirus Group B Infections during Pregnancy: An Updated Literature Review

Coxsackievirus group B (CVB), a member of the Picornaviridae family and enterovirus genus, poses risks during pregnancy due to its potential to cause severe fetal and neonatal infections.
Carolina Longo, Mauricio Saito, Heron Werner, Evelyn Traina, Pedro Teixeira Castro, Julio Elito Júnior, Edward Araujo Júnior   +6 more
core   +1 more source

Solution Structure of the Coxsackievirus and Adenovirus Receptor Domain 1^†,‡

, 2016
The coxsackievirus and adenovirus receptor (CAR) mediates entry of coxsackievirus B (CVB) and adenovirus (Ad). The normal cellular function of CAR, which is expressed in a wide variety of tissue types, is thought to involve homophilic cell adhesion in ...
Michael Caffrey (151843), Amy Jacobs (341609), Thomas M. Laue (742863), Shaokai Jiang (2724187)   +3 more
core   +1 more source