Results 111 to 120 of about 12,093 (219)

Are there functional consequences of a reduction in selenium intake in UK subjects? [PDF]

, 2004
Dietary Se levels in the UK have fallen over the last 20 years and recent surveys indicate that average Se intakes are 30-40 microg/d, which is well below the current UK reference nutrient intake for adult men (75 microg/d) or women (60 microg/d ...
Anne McArdle, Beck, Bonomini, Broome, Burk, C. Anthony Hart, Caroline S. Broome, Francis McArdle, Gasparian, Ge, Malcolm J. Jackson, Olivieri, Peretz, Stephanie A. Dillon   +13 more
core   +1 more source

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]

, 2014
Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W., Benkö M., Cauthen A.N., Crawford-Miksza L., Estrella Lopez-Gordo, Gall J., Gall J.G., Gattoni A., Ginsberg H.S., Haviv Y.S., Hofmann C., Iva I. Podgorski, Kajon A.E., Kanerva A., Kass-Eisler A., Kuriyama S., Mastrangeli A., Michou A.I., Nicholas Downes, Ramon Alemany, Rogozhin V.N., Roy S., Seiradake E., Shmarov M.M., Soudais C., Tutykhina I.L., Wang D.Y., Wohlfart C., Ying B., Zakhartchouk A.N., Zeng Q.   +30 more
core   +3 more sources

Extremely Low Organ Toxicity and Strong Antitumor Activity of miR-34-Regulated Oncolytic Coxsackievirus B3

Molecular Therapy: Oncolytics, 2019
Oncolytic virotherapies have emerged as new modalities for cancer treatment. We previously reported that coxsackievirus B3 (CVB3) is a novel oncolytic virus (OV) with a strong ability to lyse human non-small cell lung cancer cells; however, its non ...
Yang Jia, Shohei Miyamoto, Yasushi Soda, Yuto Takishima, Miyako Sagara, Jiyuan Liao, Lisa Hirose, Yasuki Hijikata, Yoshie Miura, Kenichiro Hara, Atsufumi Iwanaga, Yasunori Ota, Kenzaburo Tani   +12 more
doaj   +1 more source

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin [PDF]

, 2014
CurcumalongaL.(Zingiberaceaefamily)anditspolyphenoliccompoundcurcuminhavebeensubjectedtoavarietyofantimicrobial investigationsduetoextensivetraditionalusesandlowsideeffects.Antimicrobialactivitiesforcurcuminandrhizomeextractof C ...
AbdulKadir, Habsah, Abubakar, Sazaly, Hassandarvish, Pouya, Tajik, Hassan, Zandi, Keivan, Zorofchian Moghadamtousi, Soheil   +5 more
core   +2 more sources

Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1 [PDF]

, 2019
Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development.
Adamovich, Baggen, Bazzone, Bergelson, Berry, Bladt, Brandenburg, Carthy, Coyne, Coyne, Dodding, Donnelly, Edelman, Fernández-Puentes, Franz, Frischknecht, Fujimoto, Galisteo, Galletta, Glaser, Grøvdal, Hackett, Howlin, Huber, Innocenti, Jacobi, Jiang, Jones, Jose, Karlas, Keszei, Kim, König, Liu, Lupberger, Madshus, Madshus, Mahajan, Mahajan, Mahajan, Massaad, Melnick, Nguyen, Oppliger, Peterson, Porotto, Prieto-Echagüe, Prieto-Echagüe, Rohatgi, Rohatgi, Shen, Staring, Stradal, Teo, Wang, Winston, Wolf, Yamauchi, Yokoyama, Yokoyama, Zerbino   +60 more
core   +2 more sources

Oncolytic Virotherapy and Immunogenic Cell Death: Mechanisms, Platforms, and Clinical Translation

Viruses
Oncolytic viruses represent a paradigm-shifting approach to cancer immunotherapy, functioning as in situ vaccines that convert immunologically “cold” tumors into “hot” tumors through induction of immunogenic cell death (ICD). Despite the clinical success
Hiroyuki Inoue
doaj   +1 more source

Die Bedeutung des Low Molecular Weight Protein 7 (LMP7)- spezifischen Inhibitors ONX 0914 bei der viralen Infektion der Maus [PDF]

, 2018
Herzinsuffizienz ist eine der häufigsten Todesursachen. Ein Auslöser hierfür kann eine entzündliche Herzerkrankung sein, die durch virale Infektionen beispielsweise mit CoxsackievirusB3 ausgelöst werden können.
Goetzke, Carl Christoph
core   +1 more source

High proportion of coxsackievirus B3 genotype A in hand, foot and mouth disease in Zhenjiang, China, 2011–2016

International Journal of Infectious Diseases, 2019
Background: Hand, foot and mouth disease (HFMD) is usually caused by EVA71 and CVA16 except for a few cases that are caused by non-EVA71 non-CAV16 enteroviruses.
Xuemin Fu, Lingxiang Mao, Zhenzhou Wan, Rong Xu, Yingying Ma, Li Shen, Xia Jin, Chiyu Zhang   +7 more
doaj   +1 more source

Enterovirusten tyypitys RT-qPCR-menetelmällä [PDF]

, 1999
Työn tarkoituksena oli optimoida toimiva ja herkkä RT-qPCR-menetelmä enterovirusten tyypittämiseksi monistamalla enterovirusgenomin VP1-aluetta. Optimoinnissa käytettiin näytteinä plasmidiin kloonattuja virusgenomeja ja virus-RNA:ta, jotka oli eristetty ...
Jaume Llistosella i Vidal, Jordi Vila i Garcia, Xavier Llimona i Pagès   +2 more
core   +1 more source

ANTIGENIC ANALYSIS OF COXSACKIEVIRUS B3 WITH MONOCLONAL ANTIBODIES

Japanese Journal of Medical Science and Biology, 1993
All the 16 mouse monoclonal antibodies (McAbs) raised against Nancy strain of coxsackievirus B3, CoxB3(N), were type 3-specific. The reactivity of CoxB3(N) to this McAb panel during the serial passages showed a variation. Three field isolates of CoxB3, all neutralizable with the reference Anti-CoxB3 hyperimmune serum, were checked for the reactivities ...
H, Hu, D, Dong, E, Tang, M, Zhang, Y, Cao   +4 more
openaire   +3 more sources