Results 111 to 120 of about 8,213 (208)

Captopril suppresses interstitial fibrin deposition in coxsackievirus B3 myocarditis

, 1997
The effects of captopril on murine coxsackievirus B3 (CB3) myocarditis were investigated, with focus on interstitial fibrin deposition and changes in the connective tissue matrix. Captopril was administered intraperitoneally at a dose of 0.1 mg/g to CB3-
Y. Hiraoka, C. Kishimoto, H. Takada, M. Kurokawa, K. Shiraki, S. Sasayama   +5 more
core   +1 more source

Transplacental infection of coxsackievirus B3 pathological findings in the fetus

, 2007
Coxsackievirus intrauterine infection has been documented mostly on the basis of indirect evidence of transplacental transmission, with neonatal manifestations ranging from asymptomatic infection to meningoencephalitis, myocarditis, and generalized ...
Patsouris, E., Tsakris, A., Anninos, H., Spanakis, N., Syridou, G., Kotsiakis, X., Konstantinidou, A.   +6 more
core  

The signal transducer and activator of transcription STAT3 and coxsackievirus B3-induced chronic myocarditis

, 2011
Der Transkriptionsfaktor STAT3 ist von großer Bedeutung für die Zytoprotektion und Hypertrophie von Kardiomyozyten. STAT3 wird über den JAK/STAT Signalweg durch IL-6-ähnliche Proteine aktiviert und reguliert die Genexpression von Proteinen, die an der ...
Marggraf, Katharina
core   +1 more source

Abietic acid targets RAN to restrict coxsackievirus B3 infection

Frontiers in Microbiology
Coxsackievirus B3 (CVB3) represents a major etiological factor of viral myocarditis (VMC). It frequently results in the damage of the heart and even heart failure, but there are few effective treatment measures that can be used clinically. In this paper,
Junbo Huang, Qing Song, Yanjun Di, Zhiyun Cheng, Zhaocheng Yang, Xibo Lin, Kaiyuan Hunag, Haoyi Zhan, Lijuan Xie, Jieqing Liu, Lei Tong   +10 more
doaj   +1 more source

TF-FVIIa PAR2-β-arrestin in mouse signaling sustains organ dysfunction in coxsackievirus B3 infection [PDF]

BACKGROUND: Accumulating evidence implicates the activation of G-protein-coupled PARs (protease-activated receptors) by coagulation proteases in the regulation of innate immune responses.
Goetzke, Carl Christoph, Sauter, M., Weiler, Hartmut, Kaur, D., Bukur, T., Bukur, V., Beling, A., Grunz, Kristin, Bredow, C., Klingel, K., Sauter, Martina, Bukur, Thomas, Mülleder, Michael, Ruf, Wolfram, Ruf, W., Althof, N., Heuser, A., Kespohl, Meike, Goetzke, C.C., Kelm, N., Gaida, M.M., Kaur, Dilraj, Bredow, Clara, Berndt, Nikolaus, Althof, Nadine, Klingel, Karin, Pinkert, S., Gaida, Matthias M., Mülleder, M., Kelm, Nicolas, Pinkert, Sandra, Bukur, Valesca, Grunz, K., Heuser, Arnd, Beling, Antje, Kespohl, M., Berndt, N., Weiler, H.   +37 more
core   +1 more source

Coxsackievirus B3-Induced Myocarditis [PDF]

The American Journal of Pathology, 1998
John R. Gebhard, Christopher M. Perry, Stephanie Harkins, Thomas Lane, Ignacio Mena, Valérie C. Asensio, Iain L. Campbell, J. Lindsay Whitton   +7 more
openaire   +1 more source

Coxsackievirus B3 sequences in the myocardium of fatal cases in a cluster of acute myocarditis in Greece

, 2005
Aim: The investigation of three fatal cases during a nationwide cluster of cases of an upper respiratory tract infection (URTI) associated with myocarditis and/or pericarditis in Greece in 2002.
Manolis, EN, Tsakris, A, Panagiotopoulos, T, Tsiodras, S, Legakis, NJ, Saroglou, G, Spanakis, N   +6 more
core  

Coxsackievirus B3 and the Neonatal CNS [PDF]

The American Journal of Pathology, 2003
Ralph Feuer, Ignacio Mena, Robb R. Pagarigan, Stephanie Harkins, Daniel E. Hassett, J. Lindsay Whitton   +5 more
openaire   +1 more source

Cytoplasm Hydrogelation-Mediated Cardiomyocyte Sponge Alleviated Coxsackievirus B3 Infection

Viral myocarditis (VMC), commonly caused by coxsackievirus B3 (CVB3) infection, lacks specific treatments and leads to serious heart conditions. Current treatments, such as IFNα and ribavirin, show limited effectiveness.
Cheng Gao (463618), Dayong Gu (274142), Jingzhe Wang (4452178), Siyao Gu (17048086), Weidong Xie (344815), Hui-hui Yang (17048089), Tonggong Liu (10793187)   +6 more
core   +1 more source

Design of LNA-modified siRNAs against the highly structured 5′ UTR of coxsackievirus B3

, 2008
This study describes a strategy to develop LNA-modified small interfering RNA (siRNAs) against the highly structured 5′ UTR of coxsackievirus B3 (CVB-3), which is an attractive target site due to its high degree of conservation.
Jesper Wengel, Dutkiewicz, Mariola, Suzy W. Lena, Hans-Peter Grunert, Grunert, Hans-Peter, Mariola Dutkiewicz, Lena, Suzy W., Wengel, Jesper, Kurreck, Jens, Heinz Zeichhardt, Zeichhardt, Heinz, Jens Kurreck   +11 more
core   +1 more source