Results 101 to 110 of about 69,182 (204)
Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy
Frontiers in Pharmacology, 2018 Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury.
Yimiao Sang +13 more
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Oncolytic Virotherapy and Immunogenic Cell Death: Mechanisms, Platforms, and Clinical Translation
VirusesOncolytic viruses represent a paradigm-shifting approach to cancer immunotherapy, functioning as in situ vaccines that convert immunologically “cold” tumors into “hot” tumors through induction of immunogenic cell death (ICD). Despite the clinical success
Hiroyuki Inoue
doaj +1 more source
Journal of VirologyLysophosphatidic acid (LPA) is a bioactive signaling lipid that regulates cellular processes, including growth, survival, differentiation, and metabolic homeostasis.
Natalie J. LoMascolo +3 more
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Molecular Therapy: Oncolytics, 2019 Oncolytic virotherapies have emerged as new modalities for cancer treatment. We previously reported that coxsackievirus B3 (CVB3) is a novel oncolytic virus (OV) with a strong ability to lyse human non-small cell lung cancer cells; however, its non ...
Yang Jia +12 more
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, 2019 Enterovirus and Coxsackievirus are the major viruses that cause hand, foot, and mouth disease (HFMD) outbreaks worldwide. Several studies have shown the potential of viral envelope protein 1 (VP1) on providing protective effects from viral strains of ...
Nian-Zhi Ning (7834061) +8 more
core +1 more source
, 2019 Enterovirus and Coxsackievirus are the major viruses that cause hand, foot, and mouth disease (HFMD) outbreaks worldwide. Several studies have shown the potential of viral envelope protein 1 (VP1) on providing protective effects from viral strains of ...
Nian-Zhi Ning (7834061) +8 more
core +1 more source
Detection of coxsackievirus B3 RNA in myocardial tissues by the polymerase chain reaction
, 1991 Coxsackievirus B3 is a possible etiologic agent in some forms of myocarditis and idiopathic dilated cardiomyopathy. A method for the detection of coxsackievirus B3 RNA was developed using the polymerase chain reaction based on the amplification of a cDNA
Billingham, M. E. +3 more
core
Study on the inhibitory effect of geniposide on coxsackievirus and its mechanism
Frontiers in PharmacologyBackgroundCoxsackievirus infection can cause various diseases such as myocarditis and encephalitis, posing a serious threat to human health. However, there are currently no specific therapeutic drugs or effective vaccines for Coxsackievirus infection, so
Jianbo Xia, Zuliang Shi, Mengxin Shen
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Transplacental infection of coxsackievirus B3 pathological findings in the fetus
, 2007 Coxsackievirus intrauterine infection has been documented mostly on the basis of indirect evidence of transplacental transmission, with neonatal manifestations ranging from asymptomatic infection to meningoencephalitis, myocarditis, and generalized ...
Patsouris, E. +6 more
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SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors
, 2011 Coxsackievirus and related enteroviruses are important human pathogens that cause various diseases with clinical manifestations ranging from trivial flu-like syndromes to dangerous or even fatal diseases such as myocarditis, meningitis and encephalitis ...
Helena Mertlíková-Kaiserová +17 more
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