Results 41 to 50 of about 16,684 (160)

Evidence for coxsackievirus infection in primary Sjögren's syndrome [PDF]

open access: yesArthritis & Rheumatism, 2004
AbstractObjectivePrimary Sjögren's syndrome (SS) is an autoimmune disease characterized by activation of minor salivary gland (MSG) epithelial cells and B and T lymphocytic infiltrates. These findings have long encouraged the hypothesis that a persistent viral infection of the MSG epithelial cells may drive the autoimmune response; however, the ...
Antigoni Triantafyllopoulou   +2 more
openaire   +3 more sources

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

open access: yesPhotochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina   +3 more
wiley   +1 more source

Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]

open access: yes, 2013
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo   +47 more
core   +2 more sources

Discovery of miRNAs unique to actively transcribed erythroparvovirus infection in heart failure patients

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 1872-1882, June 2025.
Abstract Aims miRNAs, small non‐coding RNAs, play key roles in gene regulation, cell differentiation and tissue development. They influence viral infection outcomes by directly interacting with viral genomes or modifying the host microenvironment. This study demonstrates miRNAs' ability to selectively suppress transcriptionally active erythroparvovirus,
Ganna Aleshcheva   +5 more
wiley   +1 more source

Pathogenic and Molecular Characteristics of Two Isolates of HEV-B Species [PDF]

open access: yes, 2012
Enteroviruses (EVs) are small non-enveloped RNA viruses forming a large group of different serotypes. EVs belong to the family Picornaviridae. The primary replication site of an enterovirus is typically the epithelium of the respiratory tract and the ...
Al-Hello, Haider
core  

IL‐37 Mitigates the Inflammatory Response in Macrophages Induced by SARS‐CoV‐2 Omicron Infection Through the NF‐κB Signaling Pathway

open access: yesMedComm, Volume 6, Issue 6, June 2025.
IL‐37 mitigates the infiltration of macrophages and suppresses the production of macrophage‐associated chemokines (such as CCL3 and CCL4) induced by SARS‐CoV‐2 Omicron infection through NF‐κB signaling pathway. ABSTRACT The expression levels of macrophage‐associated cytokines are significantly greater in COVID‐19 patients than in healthy individuals ...
Feifei Qi   +11 more
wiley   +1 more source

Diagnostic virology. [PDF]

open access: yes, 1987
Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures.
Drew, WL
core  

Induction of cytopathic effect and cytokines in coxsackievirus B3-infected murine astrocytes [PDF]

open access: yes, 2013
BACKGROUND: Coxsackievirus commonly infects children and occasionally causes severe meningitis and/or encephalitis in the newborn. The underlying mechanism(s) behind the central nervous system pathology is poorly defined. METHODS: It is hypothesized that
Dangui Zhang   +7 more
core   +1 more source

Inflammatory Nail Disorders in Skin of Color: A Systematic Review of Clinical and Onychoscopic Manifestations

open access: yesInternational Journal of Dermatology, Volume 64, Issue 6, Page 1013-1020, June 2025.
ABSTRACT Despite increasing attention regarding skin diseases in individuals with skin of color (SoC), there remains a significant gap in understanding and identifying inflammatory nail disorders in this population. This systematic review aims to synthesize the clinical and onychoscopic features of inflammatory nail disorders in patients with SoC ...
Lea Tordjman   +3 more
wiley   +1 more source

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