Results 51 to 60 of about 3,270,007 (313)

Duffy phenotype and plasmodium vivax infections in humans and Apes, Africa [PDF]

, 2012
info:eu-repo/semantics ...
Culleton, Richard Leighton, Ferreira, Pedro Eduardo   +1 more
core   +4 more sources

Enhancement of coxsackievirus B3 infection by antibody to a different coxsackievirus strain [PDF]

Journal of General Virology, 2002
Group B coxsackieviruses (CVBs) are a major cause of viral myocarditis and pancreatitis in humans and produce a similar pattern of disease in inbred strains of mice. As there are six strains of CVBs, individuals can be infected with multiple serotypes.
Jaskamal, Girn, Mojgan, Kavoosi, Janet, Chantler   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

High‐Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15‐Specific Protease mUSP18

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
Deubiquitinases (DUBs) and Ub‐like proteases are attractive but challenging drug targets. We developed a high‐throughput synthesis method and prepared a 7536‐member cyanimide DUB‐targeted compound library in 1536‐well plates, using Echo acoustic dispensing. Screening yielded a selective, 35 nM inhibitor of mUSP18, the main ISG15 protease.
Raymond Kooij, Vito Pol, Jin Gan, Bjorn R. van Doodewaerd, Aysegul Sapmaz, Marta Campos Alonso, Günter Fritz, Klaus‐Peter Knobeloch, Paul P. Geurink   +8 more
wiley   +2 more sources

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin [PDF]

, 2014
CurcumalongaL.(Zingiberaceaefamily)anditspolyphenoliccompoundcurcuminhavebeensubjectedtoavarietyofantimicrobial investigationsduetoextensivetraditionalusesandlowsideeffects.Antimicrobialactivitiesforcurcuminandrhizomeextractof C ...
AbdulKadir, Habsah, Abubakar, Sazaly, Hassandarvish, Pouya, Tajik, Hassan, Zandi, Keivan, Zorofchian Moghadamtousi, Soheil   +5 more
core   +2 more sources

Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections

Virology Journal, 2014
BackgroundStress granules (SGs) are granular aggregates in the cytoplasm that are formed under a variety of stress situations including viral infection.
Shuo Wu, Yan Wang, Lexun Lin, X. Si, Tianying Wang, Xiaoyan Zhong, Lei Tong, Ying Luan, Yang Chen, Xiaoyu Li, Fengmin Zhang, Wenran Zhao, Zhaohua Zhong   +12 more
semanticscholar   +1 more source

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source

Coxsackievirus A9 Infects Cells via Nonacidic Multivesicular Bodies [PDF]

Journal of Virology, 2014
ABSTRACT Coxsackievirus A9 (CVA9) is a member of the human enterovirus B species in the Enterovirus genus of the family Picornaviridae . According to earlier studies, CVA9 binds to αVβ3 and αVβ6 integrins on the cell surface and utilizes β2-microglobulin, dynamin, and ...
Huttunen Moona, Marjomäki Varpu, Waris Matti, Kajander Ritva, Hyypiä Timo, Waris Matti Eliel, Kajander Ritva Brita, Hyypiä Timo Kaarlo   +7 more
openaire   +4 more sources

Neoadjuvant therapy in skin cancer: current evidence and future perspectives

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello, Johannes Kleemann, Bastian Schilling   +2 more
wiley   +1 more source