Results 121 to 130 of about 47,629 (244)
The Journal of Physiology, EarlyView.Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson +1 more
wiley +1 more source
Functional annotation clustering of differentially methylated CpG islands.
, 2012 Functional annotation clustering of differentially methylated CpG islands.
Maria G. Kapetanaki (172448) +7 more
core +1 more source
Intragenic CpG Islands and Their Impact on Gene Regulation. [PDF]
Front Cell Dev Biol, 2022 Cain JA, Montibus B, Oakey RJ.
europepmc +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain. [PDF]
Nat Commun, 2023 Becht DC +18 more
europepmc +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Histone methylation marks play important roles in predicting the methylation status of CpG islands
, 2008 The methylation status of CpG islands is highly correlated with gene expression. Current methods for computational prediction of DNA methylation only utilize DNA sequence features.
Fan, S., Zhang, X., Zhang, M. Q.
core +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley +1 more source
Enrichment of PRC proteins at hypermethylated CpG islands.
, 2013 Aggregation plots of EZH2 (upper panel) and RING1B (lower panel) ChIP-Seq signal intensities around the center of hypermethylated and hypomthylated CpG islands generated using Sitepro tool in Cistrome Analysis pipeline [42].
Fan Gao (130617) +11 more
core +1 more source
Prostate Cancer Development, Progression, and Therapy
MedComm – Oncology, Volume 5, Issue 3, September 2026.This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source