Results 241 to 250 of about 898,079 (297)

The CpG Landscape of Protein Coding DNA in Vertebrates

Evolutionary Applications, Volume 18, Issue 5, May 2025.
ABSTRACT DNA methylation has fundamental implications for vertebrate genome evolution by influencing the mutational landscape, particularly at CpG dinucleotides. Methylation‐induced mutations drive a genome‐wide depletion of CpG sites, creating a dinucleotide composition bias across the genome. Examination of the standard genetic code reveals CpG to be
Justin J. S. Wilcox, James Ord, Dennis Kappei, Toni I. Gossmann   +3 more
wiley   +1 more source

Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice. [PDF]

Genome Res
Boukas L, Luperchio TR, Razi A, Hansen KD, Bjornsson HT.   +4 more
europepmc   +1 more source

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

Nature Cell Biology, 2013
Jin-quan He, Li Shen, Ma Wan, O. Taranova, Hao Wu, Yi Zhang   +5 more
semanticscholar   +1 more source

5′ CpG island hypermethylation is associated with transcriptional silencing of the p21CIP1/WAF1/SDI1 gene and confers poor prognosis in acute lymphoblastic leukemia

, 2002
José Román‐Gómez, Juan A. Castillejo, Antonio Jiménez, Maria Gracia Gonzalez, Fernanda Moreno, Carmen García‐Rodríguez, Manuel Barrios, Juan Maldonado, António Torres   +8 more
openalex   +1 more source

Protective immune response against Rhodococcus equi: An innate immunity‐focused review

Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.
Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira, Noah D. Cohen, Sara D. Lawhon, Robert O. Watson, Angela I. Bordin   +4 more
wiley   +1 more source

Integration of multi-omics data revealed the orphan CpG islands and enhancer-dominated c is-regulatory network in glioma. [PDF]

iScience
Yao J, Yao P, Li Y, He K, Ma X, Yang Q, Jia J, Chen Z, Yu S, Gu S, Chen K, Zhao Y, Li W, Wang G, Guo M.   +14 more
europepmc   +1 more source

Global and non‐random CpG‐island methylation in gastric carcinoma associated with Epstein‐Barr virus [PDF]

, 2003
Ja‐Mun Chong, Kazuya Sakuma, Makoto Sudo, Tetsuo Ushiku, Hiroshi Uozaki, Junji Shibahara, Hideo Nagai, Nobuaki Funata, Hirokazu Taniguchi, Hiroyuki Aburatani, Masashi Fukayama   +10 more
openalex   +1 more source

Evaluating Bacillus Calmette–Guérin Polysaccharide Nucleic Acid as an Adjuvant for Influenza Vaccines in Mice

Influenza and Other Respiratory Viruses, Volume 19, Issue 5, May 2025.
ABSTRACT Background To enhance influenza vaccine efficacy, it is essential to investigate new adjuvants that are both safe and effective. In a recent study utilizing a mouse model, Bacillus Calmette–Guérin polysaccharide nucleic acid (BCG‐PSN) emerged as a promising candidate vaccine adjuvant.
Sijing Yan, Fan Yang, Jia Ji, Xiantian Lin, Ping Wang, Han Wu, Linfang Cheng, Fumin Liu, Nanping Wu, Hangping Yao, Wade S. J. Wu, Haibo Wu   +11 more
wiley   +1 more source

PCGIMA: developing the web server for human position-defined CpG islands methylation analysis. [PDF]

Front Genet
Xiao M, Xiao Y, Yu J, Zhang L.
europepmc   +1 more source

A Method for Identification of the Methylation Level of CpG Islands From NGS Data. [PDF]

Sci Rep, 2020
Uroshlev LA, Abdullaev ET, Umarova IR, Il'icheva IA, Panchenko LA, Polozov RV, Kondrashov FA, Nechipurenko YD, Grokhovsky SL.   +8 more
europepmc   +1 more source