Results 171 to 180 of about 2,100 (181)

Structural and functional study of CPSF6 in HIV-1 nuclear import

Étude structurale et fonctionnelle de CPSF6 dans l'import nucléaire du VIH-1 L'interaction du complexe CPSF5/CPSF6 avec les complexes CA du VIH-1 a été étudiée par cristallographie et cryoEM. Nos résultats montrent que CPSF5 forme un complexe étroit avec CPSF6 in vitro, ce qui peut expliquer le co-recrutement du CPSF5 avec le CPSF6 par ...
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Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

MBio, 2021
Zhou Zhong, Jiying Ning, Sooin Jang
exaly  

CPSF6 loss mediates LDHA 3’UTR shortening to promote fibroblast glycolysis and pulmonary fibrosis

Cellular Signalling
Pulmonary fibrosis is a chronic and progressive fibrotic lung disease with a poor prognosis and few treatment options. Alternative polyadenylation (APA), an important post-transcriptional regulatory mechanism, remains poorly understood in pulmonary fibrosis.
Huanyu, Yang, Mengjia, Han, Li, Zhang, Changhong, Yao, Qi, Xu   +4 more
exaly   +3 more sources

Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma

Chinese Journal of Cancer Research: Official Journal of China Anti-Cancer Association, Beijing Institute for Cancer Research, 2022
Shichao Guo, Guangchao Wang, Zitong Zhao   +2 more
exaly  

The Oncogenic Role and Potential Treatment of a Novel CPSF6-Rarg Fusion in Myeloid Transformation

Blood, 2022
Tianhui Liu, Tanzhen Wang, Lijuan Qi, Yujie Liu, Suning Chen, Yang Xu, Depei Wu   +6 more
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The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b

Journal of Biological Chemistry, 2020
Sabyasachi Dash, Muthukumar Balasubramaniam, Adrian Padron   +2 more
exaly  

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes

Journal of Biological Chemistry, 2016
Ming-Chieh Shun, Erik Serrao, Gregory A Sowd   +2 more
exaly  

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

Proceedings of the National Academy of Sciences of the United States of America, 2016
Gregory A Sowd, Erik Serrao, Hind J Fadel   +2 more
exaly  

E3 ligase SYVN1-mediated polyubiquitination of CPSF6 promotes alternative polyadenylation and antivirus effects of macrophages

Cell Reports
Anlong Xu
exaly  

CPSF6 antibody | knockout validation | Abcam ab175237 | Bethyl Laboratories A301-358A

Materials and Methods, 2016
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