Results 51 to 60 of about 781,009 (287)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Study of mechanical behavior by fatigue of a cracked plate repaired by different composite patches

Fracture and Structural Integrity, 2021
This research is based on the study of the fatigue behavior of an aluminum alloy plate with a central crack. The plate is subjected to a tensile loading on its lower and upper parts.
Moulgada Abdelmadjid, Ait kaci Djafar, Sahli Abderrahmane, Zagane Mohammed El Sallah, Zahi Rachid   +4 more
doaj   +1 more source

Dynamics and Instabilities of Planar Tensile Cracks in Heterogeneous Media

, 1997
The dynamics of tensile crack fronts restricted to advance in a plane are studied. In an ideal linear elastic medium, a propagating mode along the crack front with a velocity slightly less than the Rayleigh wave velocity, is found to exist.
B. Cotterell, B. Lawn, D. Ertaş, Daniel S. Fisher, E. S. C. Ching, G. Perrin, H. Bergkvist, J. Fineberg, J. Hodgdon, J. Morrissey, J. R. Willis, J. Schmittbuhl, L. B. Freund, M. Kardar, M. Marder, Onuttom Narayan, P. Daguier, Sharad Ramanathan   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Stress corrosion cracking in Al-Zn-Mg-Cu aluminum alloys in saline environments [PDF]

, 2012
Copyright 2013 ASM International. This paper was published in Metallurgical and Materials Transactions A, 44A(3), 1230 - 1253, and is made available as an electronic reprint with the permission of ASM International.
A. Berzin, A. Kolics, A. Turnbull, A.H. Le, A.H. Le, A.J. McEvily, A.K. Vasudevan, A.S. Tetelman, B. Jegdic, B. Sakar, B.J. Connelly, B.J. Connelly, C.A. Loto, C.M. Liao, D.J. Sullivan, D.M. Drazic, E.A. Starke, F.E. Watkinson, F.P. Ford, F.S. Lin, G. M. Scamans, G.A. Young, G.A. Young, G.M. Scamans, G.M. Scamans, H. Gruhl, H. Kim, H.F. Jong de, J. Onoro, J. Onoro, J. Robinson, J. Zhang, J.K. Park, J.P. Nordin, J.R. Scully, K. Kitamura, K. Komai, K.G. Kent, K.P. Wong, K.R. Cooper, K.R. Cooper, K.R. Cooper, L. Tomcsanyi, L.H. Chambers, L.P. Huang, M. Abe, M. Cook, M. Landkof, M. Metikos-Hukovic, M. Watanabe, M.O. Speidel, M.V. Hyatt, N. J. Henry Holroyd, N. Lampeas, N.J.H. Holroyd, N.J.H. Holroyd, N.J.H. Holroyd, O.D. Sherby, P. Martin, P.M. Natishan, R. Hermann, R.C. Doward, R.S. Pathania, R.T. Foley, R.T. Foley, S. Lee, S. Mostovoy, S. Ohsaki, S. Ohsaki, S. Osaki, S. Pyun, S. Pyun, T. Ishikawa, T. Magnin, T. Ohnishi, T. Oka, T.H. Nguyen, T.H. Nguyen, T.H. Sanders, W. Gruhl, Y. Choi, Z.A. Foroulis   +81 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

High-speed laser-directed energy deposition of crack-free wear-resistant and anti-corrosive Al/Cu bimetal components

Virtual and Physical Prototyping
Al/Cu bimetal components (BMCs) possess higher thermal conductivity, better wear resistance and corrosion resistance than Al and Al alloys. It is a big challenging task to fabricate a high-performance Al/Cu BMC by a conventional infrared (IR) laser ...
Junhao Sun, Zhuguo Li, Dongsheng Wu, Hisaya Komen, Manabu Tanaka, Joerg Volpp, Gang Luo, Yongkang Zhang, Ninshu Ma, Wei Jiao, Ke Feng   +10 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Bending by Concentrated Force of a Cantilever Strip Having a Through-thickness Crack Perpendicular to Its Axis

Applied Sciences, 2020
The article focuses on the bending problem for a cantilever beam with a straight through-thickness crack, perpendicular to its axis under bending by concentrated force.
Mykhaylo Delyavskyy, Viktor Opanasovych, Oksana Bilash   +2 more
doaj   +1 more source