The effect of thickness on fatigue crack propagation in 7475-T731 aluminum alloy sheet [PDF]
Tests were conducted on three thicknesses of 7475-T731 aluminum alloy sheet to investigate the effect of thickness on fatigue crack propagation under constant amplitude loading conditions and on retardation following a single peak overload.
Daiuto, R. A., Hillberry, B. M.
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Some experimental observations of crack-tip mechanics with displacement data [PDF]
, 2015 Estudio de la mecánica en el vértice de la grieta mediante datos de desplazamiento.In the past two decades, crack-tip mechanics has been increasingly studied with full-field techniques.
Lopez-Crespo, Pablo +3 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
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Effect of Specimen Thickness and Stress Intensity Factor Range on Plasticity-Induced Fatigue Crack Closure in A7075-T6 Alloy. [PDF]
Materials (Basel), 2021 Masuda K, Ishihara S, Oguma N.
europepmc +1 more source
Permanent indentation characterization for low-velocity impact modelling using three-point bending test [PDF]
, 2013 This paper deals with the origin of permanent indentation in composite laminates subjected to low-velocity impact. The three-point bending test is used to exhibit a non-closure of matrix crack which is assumed as a cause of permanent indentation ...
Bouvet, Christophe +3 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A study of fatigue crack closure using electric potential and compliance techniques [PDF]
Compared are closure data produced on the same specimen by the crack tip compliance gage and electric potential techniques. Experiments on 7075-T651 aluminum center cracked panels produced equivalent results on closure using the two techniques.
Cassatt, G. C., Clarke, C. K.
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A numerical analysis of the plastic wake influence on plasticity induced crack closure [PDF]
, 2017 Fatigue crack closure has been studied by means of finite element method since long time ago. Most work has been performed considering bi-dimensional models. Lately, the use of threedimensional models has been extended.
Antunes, F.V. +3 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
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Influence of fatigue crack wake length and state of stress on crack closure [PDF]
The location of crack closure with respect to crack wake and specimen thickness under different loading conditions was determined. The rate of increase of K sub CL in the crack wake was found to be significantly higher for plasticity induced closure in ...
Fisher, D. M., Telesman, J.
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