Results 71 to 80 of about 69,100 (301)

A modified crack closure integral method for calculating stress intensity factors for cracked plates subject to bending loads [PDF]

open access: yes, 1989
A method is developed to calculate strain energy release rates, G, or stress intensity factors, K, using only nodal forces and displacements from a standard finite element analysis code.
Lakshminarayana, HV   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Closure Effect of I + II Mixed-mode Crack for EA4T Axle Steel

open access: yesChinese Journal of Mechanical Engineering
The crack-closure effect is a crucial factor that affects the crack growth rate and should be considered in simulation analysis and testing. A mixed-mode I + II loading fatigue crack growth test was performed using EA4T axle steel specimens.
Shuancheng Wang   +4 more
doaj   +1 more source

Environmental fatigue in aluminum-lithium alloys [PDF]

open access: yes
Aluminum-lithium alloys exhibit similar environmental fatigue crack growth characteristics compared to conventional 2000 series alloys and are more resistant to environmental fatigue compared to 7000 series alloys.
Piascik, Robert S.
core   +1 more source

Predicting fatigue crack growth rate in a welded butt joint: The role of effective R ratio in accounting for residual stress effect [PDF]

open access: yes, 2009
A simple and efficient method is presented in this paper for predicting fatigue crack growth rate in welded butt joints. Three well-known empirical crack growth laws are employed using the material constants that were obtained from the base material ...
Servetti, Guido, Zhang, X.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Strain-energy release rate analysis of a laminate with a postbuckled delamination [PDF]

open access: yes
The objectives are to present the derivation of the new virtual crack closure technique, evaluate the accuracy of the technique, and finally to present the results of a limited parametric study of laminates with a postbuckled delamination.
Shivakumar, K. N., Whitcomb, John D.
core   +1 more source

Partial crack closure under block loading [PDF]

open access: yes, 1980
Fatigue crack propagation tests under high-low and low-high block loading sequences have been performed in aluminium alloy specimens. The tests were carried out at constant [Delta]K conditions. Two stress ratios were analysed: R = 0.05 and R = 0.4. Crack
Borrego, L. P.   +2 more
core   +2 more sources

Near-threshold fatigue propagation of physically through-thickness short and long cracks in a low alloy steel [PDF]

open access: yes, 2014
International audienceIn this paper, the near-threshold fatigue behavior of physically through-thickness short cracks and of long cracks in a low alloy steel is investigated by experiments in ambient air. Physically through-thickness short fatigue cracks
Chretien, Gaëlle   +5 more
core   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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