Results 81 to 90 of about 69,100 (301)

Identification of Relationships between Heat Treatment and Fatigue Crack Growth of αβ Titanium Alloys

Metals, 2019
This study deals with the influence of microstructure on the fatigue crack growth resistance of αβ titanium alloys: Ti-6Al-4V ELI (Extra Low Interstitial) that may compete with the conventional Ti-6Al-4V alloy in the manufacture of high ...
Vincent Renon, Gilbert Henaff, Céline Larignon, Simon Perusin, Patrick Villechaise   +4 more
doaj   +1 more source

Effects of Processing Residual Stresses on Fatigue Crack Growth Behavior of Structural Materials: Experimental Approaches and Microstructural Mechanisms [PDF]

, 2012
Fatigue crack growth mechanisms of long cracks through fields with low and high residual stresses were investigated for a common structural aluminum alloy, 6061-T61.
A.K. Vasudevan, Christopher J. Lammi, D.A. Lados, D.H. Lee, D.L Chen, Diana A. Lados, F. Bergner, J.C. Newman Jr, L.P. Borrego, L.P. Borrego, M. Beghini, P.C. Paris, R.H. Christensen, S.R. Daniewicz, W. Elber, Y.C. Lam   +15 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Investigation of the Damage Mechanisms Influencing the Short Crack Behavior of Inconel 625 Under Variable Amplitude Fatigue Loading

Aerospace
Variable amplitude fatigue loading can result in both accelerated and decelerated fatigue damage due to load interaction effects. Short fatigue cracks in particular exhibit a wide range of crack growth behavior due to multiple damage mechanisms ...
Robert Fleishel, Reza Abedi, Stephanie TerMaath   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Controlling fatigue crack paths for crack surface marking and growth investigations

Fracture and Structural Integrity, 2015
While it is well known that fatigue crack growth in metals that display confined slip, such as high strength aluminium alloys, develop crack paths that are responsive to the loading direction and the local microstructural orientation, it is less well ...
S. Barter, P. White, M. Burchill
doaj   +3 more sources

Applications and Life Cycle Assessment of Shape Memory Polyethylene Terephthalate in Concrete for Crack Closure. [PDF]

Polymers (Basel), 2022
Maddalena R, Sweeney J, Winkles J, Tuinea-Bobe C, Balzano B, Thompson G, Arena N, Jefferson T.   +7 more
europepmc   +1 more source

Through-the-thickness fatigue crack closure behavior in an aluminum alloy [PDF]

The variation in fatigue crack closure behavior across the thickness of aluminum alloy specimens was investigated. The specimen geometries examined were the middle crack tension M(T) and compact tension C(T).
Dawicke, D. S., Grandt, A. F., Jr., Newman, J. C., Jr.   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

In situ measurement of fatigue crack opening stresses by nonlinear vibro-acoustic modulation testing

Advances in Mechanical Engineering, 2017
The difficulty of accurately measuring crack closure regions has hindered measurements of opening or closure stresses, and ultrasonic methods have shown great potentialities in evaluating closure area. Many recent researches have confirmed the advantages
Jun Jia, Haifeng Hu, Limin Tao, Yongpan Hu   +3 more
doaj   +1 more source