Results 91 to 100 of about 69,100 (301)
Research on the Evolution Law Physical Short Fatigue Crack and Tip Deformation Fields during Crack Closure Process of the Q&P Steel. [PDF]
Materials (Basel), 2022 Shang H, Lin Z, Gao H, Shan X, Zhan J.
europepmc +1 more source
A finite element analysis of fatigue crack closure [PDF]
Experiments have shown that fatigue cracks close at positive loads during constant-amplitude load cycling. The crack-closure phenomenon is caused by residual plastic deformations remaining in the wake of an advancing crack tip.
Newman, J. C., Jr.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Effect of Underload Cycles on Oxide-Induced Crack Closure Development in Cr-Mo Low-Alloy Steel. [PDF]
Materials (Basel), 2021 Pokorný P +4 more
europepmc +1 more source
Closure of fatigue cracks at high strains [PDF]
Experiments were conducted on smooth specimens to study the closure behavior of short cracks at high cyclic strains under completely reversed cycling. Testing procedures and methodology, and closure measurement techniques, are described in detail.
Dowling, N. E., Iyyer, N. S.
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Numerical Simulation of the Effect of Pre-Strain on Fatigue Crack Growth in AA2024-T351
MetalsThe objective here is to study the effect of pre-strain on fatigue crack growth (FCG) in 2024-T351 aluminum alloy. Three pre-strain conditions were considered: without pre-strain, compressive and tensile permanent pre-strains of 4%.
Diogo M. Neto +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Effect of Specimen Thickness and Stress Intensity Factor Range on Plasticity-Induced Fatigue Crack Closure in A7075-T6 Alloy. [PDF]
Materials (Basel), 2021 Masuda K, Ishihara S, Oguma N.
europepmc +1 more source
The effect of thickness on fatigue crack propagation in 7475-T731 aluminum alloy sheet [PDF]
Tests were conducted on three thicknesses of 7475-T731 aluminum alloy sheet to investigate the effect of thickness on fatigue crack propagation under constant amplitude loading conditions and on retardation following a single peak overload.
Daiuto, R. A., Hillberry, B. M.
core +1 more source