Results 101 to 110 of about 757,673 (217)
The Role of Meprins on the Brain Extracellular Matrix and Perineuronal Nets
Meprin β overexpression is implicated in Alzheimer's Disease. Recent studies identified brevican as a meprin β substrate, and this study demonstrates that meprin α co‐expression enhances meprin β‐mediated brevican cleavage. Further, neurocan and RPTPζ were identified as novel meprin β substrates in an N‐terminomics analysis of meprin β transgenic mice,
Simon Kreiselmaier +13 more
wiley +1 more source
A qualitative study of psychological stress and coping among persons using crack cocaine
Background Research has identified a strong link between stress and drug use behaviours. Also, it has been established that the prolonged use of crack cocaine stimulates emotional, cognitive, neurological and social changes.
Yaa Asuaba Duopah +3 more
doaj +1 more source
The striatum and thalamus are subcortical structures intimately involved in addiction. The morphology and microstructure of these have been studied in murine models of cocaine addiction (CA), showing an effect of drug use, but also chronological age in ...
E. Garza-Villarreal +11 more
semanticscholar +1 more source
ABSTRACT The relationship between trauma and addictive behaviors is well‐established, yet factors mediating this relationship remain understudied. Given the prevalence of addictive behaviors among collegiate populations, we used path analysis to explore the mediating role of arousal dysregulation in the relationship between childhood trauma and a ...
Amanda L. Giordano +3 more
wiley +1 more source
Crack cocaine in the Dublin region: an evidence base for a crack cocaine strategy. HRB Research Series 6. [PDF]
Crack cocaine is produced from powder cocaine using readily available chemical agents such as ammonia or baking soda. Smoking crack is a highly efficient way of getting cocaine into the brain, making its use compulsive and difficult to control in some ...
Long, Jean +4 more
core
Risk Factors in the Relationship Between Gender and Crack/Cocaine
Female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than on any other drug. Additionally, female inner-city substance users evidence greater crack/cocaine use and are more likely to be ...
Bornovalova, Marina +4 more
core +1 more source
Levamisole tainted cocaine causing severe neutropenia in Alberta and British Columbia
Background Five cases of severe neutropenia (neutrophil counts < 0.5 per 109 cells/L) associated with exposure to cocaine and levamisole, an antihelimithic agent no longer available in Canada, were identified in Alberta in 2008.
Fan Shihe +7 more
doaj +1 more source
Pregnancy and postpartum cannabis and alcohol use among people with HIV in the United States
Abstract Objective To evaluate patterns of alcohol and cannabis use in pregnancy and postpartum and identify associated factors in a large, diverse cohort of people with HIV. Methods We analyzed data on cannabis and alcohol use from the Surveillance Monitoring for ART Toxicities study, which enrolled pregnant people with HIV at 22 United States sites ...
Jecca R. Steinberg +11 more
wiley +1 more source
Abstract Background and aims Incidence and severity of opioid‐associated skin and soft‐tissue infections, often requiring intensive and costly medical care, have increased substantially since the emergence of xylazine in the US drug supply. Although progress has been made in clinical and harm reduction recommendations for treating xylazine‐related ...
Danielle German +9 more
wiley +1 more source

