Effect of crack closure on non-linear crack tip parameters [PDF]
, 2015 Crack closure concept has been widely used to explain different issues of fatigue crack propagation. However, some authors have questioned the relevance of crack closure and have proposed alternative concepts.
Sousa, T. +3 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Features of destruction of a ferrite-martensitic composite
MATEC Web of Conferences, 2018 The behavior of a crack in steel with the structure of a ferriticmartensitic composite is studied. The modes of heat treatment for obtaining a composite structure with alternating layers of ferrite and martensite are given.
Pustovoit Viktor N. +5 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Energy evolution and crack development characteristics of sandstone under freeze-thaw cycles by digital image correlation. [PDF]
PLoS One, 2023 Ma J, Jin J, Feng J, Qin Z.
europepmc +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Study on the Development Rule of Mudstone Cracks in Open-Pit Mine Dumps Improved with Xanthan Gum
Applied SciencesThe stability of open-pit mine slopes is crucial for safety, especially for spoil dump slopes, which are prone to cracks leading to landslides. This study investigates the use of xanthan gum (XG) to enhance the stability of mudstone in spoil dumps ...
Xiang Qi +4 more
doaj +1 more source
Model of acoustic emission signal at self‐accelerated crack development
Aviation, 2005 The article is devoted to the theoretical analysis the problem of acoustic emission signals application for the detection of self‐accelerated crack development.
Vitalii Babak +2 more
doaj +1 more source
Effect of Basalt Fiber Content and Length on the Strength and Crack Development of Polyvinyl Alcohol/Basalt Hybrid Fiber-Reinforced Cement Soil. [PDF]
Polymers (Basel), 2023 Shu Y, Zhang J.
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source