Results 81 to 90 of about 15,676,159 (315)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Materials Research ExpressThe static demolition of structures via soundless chemical demolition agent (SCDA) is attracting increasing attention because of its environmental friendliness and safety, especially in the dense urban areas.
Jinshan Sun +5 more
doaj +1 more source
BuildingsThis study investigates modular low-rise shear walls by designing and fabricating four in-plane loaded specimens at a scale ratio of 1:2.7. Quasi-static low-cycle reversed loading tests combined with numerical simulations were systematically conducted to
Hong Chang, Wei Zhou, Changhai Zhai
doaj +1 more source
Financing the Future with the IDB Group [PDF]
, 2019 Mobilizing resources is critical to the implementation of the 2030 Agenda and multilateral development banks in particular have been called upon to crowd-in additional financing for the Sustainable Development Goals (SDGs).
Inter-American Development Bank
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Development of a Finite Element Analysis Methodology for the Propagation of Delaminations in Composite Structures [PDF]
, 2006 Analysing the collapse of skin-stiffened structures requires capturing the critical phenomenon of skin-stiffener separation, which can be considered analogous to interlaminar cracking.
Degenhardt, Richard +4 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BiogeotechnicsRepeated wet swelling and dry shrinkage of soil leads to the gradual occurrence of cracks and the formation of a complex fracture network. In order to study the development characteristics and quantitative analysis of cracks in root-soil complex in ...
Zhengjun Mao +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source