Results 51 to 60 of about 7,508,587 (309)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Fatigue failure analysis of pin-loaded lugs [PDF]

open access: yesFracture and Structural Integrity, 2016
In the present paper, mathematical models are proposed in order to analyze the strength of pinloaded lugs with semi-elliptical crack and through-the-thickness crack.
Slobodanka Boljanović   +1 more
doaj   +1 more source

Numerical Simulation on Crack–Inclusion Interaction for Rib-to-Deck Welded Joints in Orthotropic Steel Deck

open access: yesMetals, 2023
Weld defects such as porosity, inclusion, burn-through, and lack of penetration are difficult to detect and control effectively in an orthotropic steel deck (OSD), which will be a fatigue crack initiation site and lead to several fatigue cracking.
Yuan Luo   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fracture toughness and fatigue crack growth rate properties in wire + arc additive manufactured Ti-6Al-4V

open access: yes, 2017
This paper presents an experimental investigation of the fracture and fatigue crack growth properties of Ti-6Al-4V produced by the Wire + Arc Additive Manufacture (WAAM®) process. First, fracture toughness was measured for two different orientations with
Xiang Zhang   +4 more
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Crack-Configuration Analysis of Metal Conductive Track Embedded in Stretchable Elastomer

open access: yesMicromachines, 2018
This paper reports the analysis of the crack configuration of a stretched metal conductive track that is embedded in a stretchable elastomer. The factor determining the crack configurations is analyzed by modeling as well as experiments.
Tomoya Koshi, Eiji Iwase
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Controlling fatigue crack paths for crack surface marking and growth investigations [PDF]

open access: yesFracture and Structural Integrity, 2016
While it is well known that fatigue crack growth in metals that display confined slip, such as high strength aluminium alloys, develop crack paths that are responsive to the loading direction and the local microstructural orientation, it is less well ...
S. Barter, P. White, M. Burchill
doaj  

Home - About - Disclaimer - Privacy