Results 71 to 80 of about 69,564 (313)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A fatigue multi-site cracks model using coalescence, short and long crack growth laws, for anodized aluminum alloys [PDF]
, 2010 It has been shown that decrease of the fatigue life of aluminium alloys treated with anodization can be explained by the degradation of surface condition due to pickling.
Chaussumier, Michel +9 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Crack growth resistance in nuclear graphite [PDF]
, 2002 R-curve behaviour is often used for evaluating crack growth resistance in quasibrittle materials but few studies have focused on polycrystalline graphite. In this study, R-curve behaviour in three commercial grade nuclear graphites, of varying structure
Fazluddin, Shahed
core
Effects of graphite nodules on crack growth behaviour of austempered ductile iron [PDF]
, 2007 Austempered ductile iron (ADI) is a candidate material for camshafts, where however, the early stages of fatigue damage are of major concern during service.
Reed, P.A.S., Gao, N., Stokes, B.
core +1 more source
R-curve Evaluation of Copper and Nickel Single Crystals Using Atomistic Simulations
Crystals, 2018 The technique of molecular statics (MS) simulation was employed to determine the crack growth resistance curve of Cu and Ni single crystals. Copper and Ni single crystal nanoplates with an edge crack subjected to a tensile displacement were simulated ...
Xiao Ru Zhuo +2 more
doaj +1 more source
Metals, 2020 In this paper, the interactions between double cracks with a co-bisector-line were investigated theoretically and experimentally. Fatigue crack growth tests of specimens with a single crack or double cracks were carried out to measure the crack growth ...
Zhichao Han, Caifu Qian, Huifang Li
doaj +1 more source
Quasistatic Growth of Cavities and Cracks in the Plane
SIAM Journal on Mathematical AnalysisWe propose a model for quasistatic growth of cavities and cracks in two-dimensional nonlinear elasticity. Cavities and cracks are modeled as discrete and compact subsets of a planar domain, respectively, and deformations are defined only outside of cracks.
Marco Bresciani, Manuel Friedrich
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source