Results 71 to 80 of about 323,428 (307)

STATISTICAL ANALYSIS OF FATIGUE CRACK GROWTH TEST DATA FOR 2024-T62 ALUMINUM ALLOY

open access: yesJixie qiangdu, 2019
The fatigue crack growth tests for 2024-T62 aluminum alloy were conducted under three stress levels, the dispersion of fatigue crack growth were analyzed by using experimental data based on mathematical statistics.
WANG XuHu   +3 more
doaj  

Influence of Grain Boundary on the Fatigue Crack Growth of 7050-T7451 Aluminum Alloy Based on Small Time Scale Method

open access: yesAdvances in Materials Science and Engineering, 2016
Based on the small time scale method, the influence of grain boundary on the fatigue crack growth of 7050-T7451 has been investigated. The interaction between fatigue crack and grain boundary was investigated by in situ SEM testing.
Weihan Wang   +4 more
doaj   +1 more source

Method of arresting crack growth for application at a narrow working space

open access: yesMechanical Engineering Journal, 2014
The many fracture accidents in engineering applications are related to fatigue crack initiation and growth. Therefore, the inspection of fatigue crack initiation and the arrest of crack growth are very important for the safe operation of a machine and ...
Chobin MAKABE   +2 more
doaj   +1 more source

Short crack initiation and growth at 600 °C in notched specimens of Inconel718

open access: yes, 2003
The natural initiation and growth of short cracks in Inconel®718 U-notch specimens has been studied at 600 °C in air. U notches were introduced through broaching, and hardness traces and optical microscopy on cross-sections through the U notch broaching ...
Connolley, T.   +2 more
core   +1 more source

A predictive fatigue life model for anodized 7050 aluminium alloy [PDF]

open access: yes, 2013
The objective of this study is to predict fatigue life of anodized 7050 aluminum alloy specimens. In the case of anodized 7050-T7451 alloy, fractographic observations of fatigue tested specimens showed that pickling pits were the predominant sites for ...
Chaussumier, Michel   +4 more
core   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

In-situ SEM and optical microscopy testing for investigation of fatigue crack growth mechanism under overload

open access: yesMATEC Web of Conferences, 2018
In this paper, the in-situ scanning electron microscope (SEM) and optical microscopy experiments are performed to investigate the crack growth behavior under the single tensile overload. The objectives are to (i) examine the overload-induced crack growth
Zhang Wei, Cai Liang
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

R-curve Evaluation of Copper and Nickel Single Crystals Using Atomistic Simulations

open access: yesCrystals, 2018
The technique of molecular statics (MS) simulation was employed to determine the crack growth resistance curve of Cu and Ni single crystals. Copper and Ni single crystal nanoplates with an edge crack subjected to a tensile displacement were simulated ...
Xiao Ru Zhuo   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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