Results 61 to 70 of about 69,564 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fail-safe design of integral metallic aircraft structures reinforced by bonded crack retarders [PDF]

open access: yes, 2009
This paper presents an investigation on the effectiveness of crack growth retarders bonded to integral metallic structures. The study was performed by both numerical modelling and experimental tests.
Irving, Phil E.   +9 more
core   +1 more source

Controlling fatigue crack paths for crack surface marking and growth investigations [PDF]

open access: yesFracture and Structural Integrity, 2016
While it is well known that fatigue crack growth in metals that display confined slip, such as high strength aluminium alloys, develop crack paths that are responsive to the loading direction and the local microstructural orientation, it is less well ...
S. Barter, P. White, M. Burchill
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Predicting fatigue crack growth life for cold-worked holes based on existing closed-form residual stress models. [PDF]

open access: yes, 2003
This paper studies the capability of four closed-form solutions for calculating cold expansion-induced residual stresses. The aim is to check whether these models are able to provide accurate solutions of residual stresses for three aerospace grade ...
Wang, Z., Zhang, Xiang
core   +1 more source

Crack-Configuration Analysis of Metal Conductive Track Embedded in Stretchable Elastomer

open access: yesMicromachines, 2018
This paper reports the analysis of the crack configuration of a stretched metal conductive track that is embedded in a stretchable elastomer. The factor determining the crack configurations is analyzed by modeling as well as experiments.
Tomoya Koshi, Eiji Iwase
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]

open access: yes, 2003
An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core  

ON CRACK CLOSURE IN FATIGUE CRACK GROWTH

open access: yes, 1978
A brief review of the various forms of closure is given, and the relative importance of plasticity-induced closure and roughness-induced closure is considered. On the basis of the lack of a thickness effect and an insensitivity to R in the absence of closure it is concluded that plasticity-induced closure plays a relatively minor role in affecting the ...
openaire   +2 more sources

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