Results 61 to 70 of about 323,428 (307)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Slow crack growth : models and experiments [PDF]

open access: yes, 2007
The properties of slow crack growth in brittle materials are analyzed both theoretically and experimentally. We propose a model based on a thermally activated rupture process.
Ciliberto, Sergio   +2 more
core   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Study of the Shielding Interactions between Double Cracks on Crack Growth Behaviors under Fatigue Loading

open access: yesMetals, 2020
In this paper, the interactions between double cracks with a co-bisector-line were investigated theoretically and experimentally. Fatigue crack growth tests of specimens with a single crack or double cracks were carried out to measure the crack growth ...
Zhichao Han, Caifu Qian, Huifang Li
doaj   +1 more source

Understanding fast macroscale fracture from microcrack post mortem patterns [PDF]

open access: yes, 2011
Dynamic crack propagation drives catastrophic solid failures. In many amorphous brittle materials, sufficiently fast crack growth involves small-scale, high-frequency microcracking damage localized near the crack tip.
Buehler   +11 more
core   +5 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Crack growth measured on flat and curved surfaces at cryogenic temperatures [PDF]

open access: yes, 1967
Multiple element continuity gage measures plane stress crack growth plus surface crack growth under plane strain conditions.
Orange, T. W., Sullivan, T. L.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An axial crack growth prediction procedure initiated at butt welded joint (Growth prediction for surface crack deeper than semi-circular and that retarded at weld fusion line)

open access: yesNihon Kikai Gakkai ronbunshu, 2018
Structural integrity of cracked pipes is assessed by predicting crack growth. In the fitness-for-service code of the Japan Society of Mechanical Engineers (JSME), the crack growth is predicted using stress intensity factor at the deepest and surface ...
Masayuki KAMAYA
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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