Results 91 to 100 of about 230,446 (308)

Prediction of fatigue crack-growth patterns and lives in three-dimensional cracked bodies [PDF]

Fatigue crack growth patterns and lives for surface cracks, surface cracks at holes, and corner cracks at holes in three dimensional bodies were predicted using linear-elastic fracture mechanics concepts that were modified to account for crack-closure ...
Newman, J. C., Jr., Raju, I. S.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Fatigue crack propagation behaviour in wire+arc additive manufactured Ti‐6Al‐4V: Effects of microstructure and residual stress [PDF]

, 2016
Fatigue crack propagation tests of Ti‐6Al‐4V fabricated by the Wire+Arc Additive Manufacturing (WAAM) process are analysed. Crack growth rate and trajectory are examined before and after the crack tip crossing an interface between the WAAM and wrought ...
ABAQUS 6.13, Addison, Almeida, Antonysamy, Antonysamy, ASTM E647-13, Baufeld, Baufeld, Baufeld, Brandl, Che-Haron, Cheng, Colegrove, Dattoma, Ding, Edwards, Edwards, Ezugwu, Frazier, Gurney, Hills, Hosseinzadeh, Kelly, Kelly, Li, Liu, Lorant, Lutjering, Martina, Paradowska, Prime, Prime, Prime, Rangaswamy, Schroeder, Shiomi, Taminger, Wang, Wang, Wang, Zhang   +40 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EXPERIMENT STUDY ON CRACK GROWTH RATE OF ADB610 STEEL UNDER DIFFERENT STRESS RATIOS

Jixie qiangdu, 2016
The test of the fatigue crack growth rate under five stress ratios（ R = 0. 1,0. 2,0. 3,0. 4 and 0. 5） is completed used the compact tensile specimen. The test data are processed by using incremental polynomial method and the expressions and curves of ...
WEI Long, WANG ShiYue, LIU GuoShou, YANG XiJie   +3 more
doaj  

Investigation of the Combined Influence of Temperature and Humidity on Fatigue Crack Growth Rate in Al6082 Alloy in a Coastal Environment. [PDF]

Materials (Basel), 2023
Alqahtani I, Starr A, Khan M.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Fatigue Crack Growth Rate Description of RF-Plasma-Sprayed Refractory Metals and Alloys. [PDF]

Materials (Basel), 2023
Kovarik O, Cizek J, Klecka J.
europepmc   +1 more source

Low Temperature Fatigue Crack Growth Test and Life Estimation of 7475-T7351 Al-ally by ANN [PDF]

, 2016
In the present wok fatigue crack growth tests have been performed under interspersed mode-I overload on 7475-T7351 Al-alloy. The overloads with an overload ratio of 2 were given at 0C, ndash;30C, ndash;45C, ndash;60C, and ndash;75C at a loading rate of 7
Mohanty, J. R. (J)
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source