Results 91 to 100 of about 652,868 (246)
The Initiation Characteristics of Corrosion Fatigue Crack in 18Ni (250) Steel
Journal of Marine Science and EngineeringMaraging steel is the material of deep sea pressure equipment. The characteristics of corrosion fatigue crack initiation in 18Ni (250) were investigated by performing a tensile fatigue test under different loading conditions.
Hongzhang Pan +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Fatigue crack growth in thin notched woven glass composites under tensile loading. Part I: experimental [PDF]
, 2011 Helicopter blades are made of composite materials mainly loaded in fatigue and have normally relatively thin skins. A through-the-thickness crack could appear in these skins.
Barrau, Jean-Jacques +7 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
MetalsThe role of notch geometry and stress levels on fatigue crack initiation and small crack propagation behavior in the FGH96 superalloy was investigated using groove and bolt hole simulated specimens at 500 °C.
Zuopeng Zhao, Xuteng Hu, Zhiwei Guo
doaj +1 more source
In Situ Fatigue Crack Analysis of 590 Wheel Steel in Different States
工程科学与技术, 2023 Fatigue crack is the main failure course of wheel steels, but its relationship with microstructure, texture, welding process and deformation remains unclear.
Ning CAI +5 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Effect of Microstructure on the Very High Cycle Fatigue Behavior of Ti-6Al-4V Alloy
MetalsCrack initiation plays a major role in very high cycle fatigue (VHCF) life, and the initiation of cracks is related to slip behavior. There is a need for improvement in the understanding of the influence of Ti-6Al-4V microstructures on VHCF performance ...
Mingyang Yuan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source