Results 81 to 90 of about 652,868 (246)
Effect on Fatigue Performance of Residual Stress induced via Laser Shock Peening in Mechanically Damaged 2024‐T351 Aluminium Sheet [PDF]
, 2014 During manufacture and maintenance the fuselage skin of aircraft are susceptible to damage in the form of scratches. Normally not considered to be of major concern to aircraft structural integrity some airlines discovered fatigue cracks had initiated ...
Smyth, Niall
core +4 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Hangkong gongcheng jinzhanThe rubbing of the labyrinth sealing structure is a common problem during the operation of aeroengine air system. Due to the difficulty in observing the process of crack initiation and propagation on the sealing ring during actual rubbing，using finite ...
CHANG Jiaqi +5 more
doaj +1 more source
Advances in Mechanical Engineering, 2017 With the focus on the failure of single-cracked rocks under compression–shear stress, the form and the critical conditions of crack initiation by adopting theoretical derivation and numerical experiments methods are researched in this article.
Ling Yue +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
WEAR AND CRACK initiation PREDICTION OF RAIL IRREGULARITY WELDING ZONE
Jixie qiangduIn order to investigate the relationship between abrasion and crack initiation in the welded zone of rails and axle weight and friction coefficient， through the field measurement of a large number of uneven weld zones， two kinds of typical weld zone ...
WEAR AND +1 more
doaj
Jixie chuandong, 2022 The fatigue crack initiation direction of wind turbine gearbox bearings is investigated. Through theoretical research，it is believed that the direction of crack initiation depends on the direction of the maximum shear stress amplitude plane at the local ...
Haibo Sun, Feng Shen
doaj
Applied Sciences, 2019 Crack propagation produced by frost heave affects the durability of slab-track structures in high-humidity and cold regions in China. This work is intended to reveal the evolution laws of frost-heave crack propagation, establish evaluation criteria for ...
Fengzhuang Tong +5 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source