Results 81 to 90 of about 42,379 (316)

Research on the influence of high speed labyrinth rubbing on the initiation and propagation of crack in sealing ring

Hangkong gongcheng jinzhan
The rubbing of the labyrinth sealing structure is a common problem during the operation of aeroengine air system. Due to the difficulty in observing the process of crack initiation and propagation on the sealing ring during actual rubbing，using finite ...
CHANG Jiaqi, LI Huidong, XIE Wenbo, MU Qinqin, CHEN Yonghui, YANG Weihua   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Influence of oxide films on primary water stress corrosion cracking initiation of alloy 600 [PDF]

, 2006
In the present study alloy 600 was tested in simulated pressurised water reactor (PWR) primary water, at 360 °C, under an hydrogen partial pressure of 30 kPa. These testing conditions correspond to the maximum sensitivity of alloy 600 to crack initiation.
Panter, J., Andrieu, Eric, Cloué, Jean-Marc, Foucault, M., Combrade, P., Viguier, Bernard, Cloué, J.M   +6 more
core   +1 more source

Study on Internal Fatigue Crack Initiation and Propagation Direction of Wind Turbine Gearbox Bearings

Jixie chuandong, 2022
The fatigue crack initiation direction of wind turbine gearbox bearings is investigated. Through theoretical research，it is believed that the direction of crack initiation depends on the direction of the maximum shear stress amplitude plane at the local ...
Haibo Sun, Feng Shen
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Research on crack initiation mechanism and fracture criterion of rock-type materials under compression–shear stress

Advances in Mechanical Engineering, 2017
With the focus on the failure of single-cracked rocks under compression–shear stress, the form and the critical conditions of crack initiation by adopting theoretical derivation and numerical experiments methods are researched in this article.
Ling Yue, Shaorui Sun, Jiaming Liu, Jihong Wei, Jimin Wu   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Experimental and Theoretical Determination of the Frost-Heave Cracking Law and the Crack Propagation Criterion of Slab Track with Water in the Crack

Applied Sciences, 2019
Crack propagation produced by frost heave affects the durability of slab-track structures in high-humidity and cold regions in China. This work is intended to reveal the evolution laws of frost-heave crack propagation, establish evaluation criteria for ...
Fengzhuang Tong, Liang Gao, Xiaopei Cai, Yanglong Zhong, Wenqiang Zhao, Yichen Huang   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]

, 2003
An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core